Results 101 to 110 of about 156,401 (247)
Challenges in the management of Phenylketonuria in Malta [PDF]
Phenylketonuria (PKU) is a rare metabolic disorder comprising a number of different enzyme deficiencies. In Malta, dihydropteridine reductase (DHPR) deficiency appears to be more common than phenylalanine hydroxylase deficiency (classical PKU), and is ...
Attard Montalto, Simon, Attard, Stephen
core
The enzyme acetylcholinesterase (AChE) is an important part of cholinergic nervous system, where it stops neurotransmission by hydrolysis of the neurotransmitter acetylcholine.
Rene Kizek+2 more
doaj +1 more source
The transporter-like protein inebriated mediates hyperosmotic stimuli through intracellular signaling [PDF]
We cloned the inebriated homologue MasIne from Manduca sexta and expressed it in Xenopus laevis oocytes. MasIne is homologous to neurotransmitter transporters but no transport was observed with a number of putative substrates.
Chiu, Chi-Sung+4 more
core
Contribution of Cystine-Glutamate Antiporters to the Psychotomimetic Effects of Phencyclidine [PDF]
Altered glutamate signaling contributes to a myriad of neural disorders, including schizophrenia. While synaptic levels are intensely studied, nonvesicular release mechanisms, including cystine–glutamate exchange, maintain high steady-state glutamate ...
A Baskys+78 more
core +2 more sources
Biophysics of risk aversion based on neurotransmitter receptor theory [PDF]
Decision under risk and uncertainty has been attracting attention in neuroeconomics and neuroendocrinology of decision-making. This paper demonstrated that the neurotransmitter receptor theory-based value (utility) function can account for human and animal risk-taking behavior.
arxiv
Computational modeling of neuronal networks [PDF]
Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in the postsynaptic neurons.
arxiv
A Polyunsaturated Fatty Acid (PUFA) Theory of Schizophrenia [PDF]
I present a theory of schizophrenia (SZ) that mechanistically explains its etiology, symptoms, pathophysiology, and treatment. SZ involves the chronic release of membrane polyunsaturated fatty acids (PUFAs) and their utilization for the synthesis of stress-induced plasticity agents such as endocannabinoids (ECBs).
arxiv
Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management
Michele Fornaro, Matteo MartinoDepartment of Neuroscience, Section of Psychiatry, University of Genova, Genova, ItalyBackground: Subjective tinnitus is a frequent, impairing condition, which may also cause neurotransmitter imbalance at the cochlea ...
Michele Fornaro, Matteo Martino
doaj
The Price of Cognition and Replicator Equations in Parallel Neural Networks [PDF]
In this paper, we are aiming to propose a novel mathematical model that studies the dynamics of synaptic damage in terms of concentrations of toxic neuropeptides/neurotransmitters during neurotransmission processes. Our primary objective is to employ Wardrop's first and second principles within a neural network of the brain. In order to comprehensively
arxiv
Hypocretin neurotransmitter system and narcolepsy [PDF]
Lakočević Milan B., Rajšić Nenad R.
doaj +1 more source