Results 121 to 130 of about 119,386 (177)
Neurotoxic and Neurotrophic Effects of GABAergic Agents on Developing Neurotransmitter Systems
, 1998 Jean M Lauder
exaly +5 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Development of anti-obesity agents: drugs that target neuropeptide and neurotransmitter systems
Expert Opinion on Investigational Drugs, 2008Obesity results from an imbalance of energy intake and energy expenditure. While the prevalence of obesity is increasing and the negative impact on public health is being recognized, highly effective and safe therapy for obesity is not yet available.This review summarizes the current state of the art in the late-stage development area of anti-obesity ...
Tung M Fong
exaly +3 more sources
Effect of antidepressant agents on β-adrenergic receptor and neurotransmitter regulatory systems
Pharmacology Biochemistry and Behavior, 1980 Abstract The effects of established and several novel antidepressant agents on brain monoamine oxidase A and B; high affinity synaptosomal uptake of norepinephrine, dopamine and serotonin; and β-adrenergic receptor kinetics evaluated by (3H)-dihydroalprenolol binding to cortical membranes are described.
Laurence R. Meyerson +3 more
openalex +3 more sources
Chemotherapeutic agents do not interact with neurotransmitter receptors
Cancer Chemotherapy and Pharmacology, 1987 The interactions of cisplatin, 5-fluorouracil, doxorubicin, mitomycin, carmustine (BCNU), cyclophosphamide, methotrexate and thio-TEPA were assessed at three neurotransmitter receptor binding sites. Each drug was inactive at concentrations as high as 10(-4) M in displacing the specific binding of 3H-spiperone to dopamine D2, 3H-pyrilamine to histamine ...
StephenJ. Peroutka
openalex +3 more sources
Neurotransmitter Interactions and Responsivity to Cholinomimetic Agents
, 1992 There is now overwhelming evidence for the involvement of forebrain cholinergic systems in Alzheimer’s disease and the cognitive processes that subserve learning and memory (Perry et al., 1978; Bigl et al., 1987; Koshimura et al., 1987; Doucette et al., 1986; Ichimiya et al., 1986; Saper et al., 1985;Whitehouse, 1986; McGeer et al., 1984; Mann et al ...
Vahram Haroutunian +2 more
openalex +2 more sources
A catecholamine neurotransmitter: epinephrine as a CO 2 wet scrubbing agent
Chemical Communications, 2019 Adrenaline can be used to capture CO2 when dissolved in DMSO.
Ala’a F. Eftaiha +4 more
openalex +3 more sources
Life Sciences, 1974 Abstract The effects of norepinephrine, other catecholamines, α- and β- adrenergic receptor blocking agents and acetylcholine on the incorporation of 32Pi into phospholipids of the iris muscle of the rabbit were studied in vitro . There was a marked stimulation of 32Pi into phosphatidic acid (PhA), phosphatidyl inositol (PhI) and to a much ...
Ata A. Abdel‐Latif
openalex +3 more sources
Species variation in the cerebrovascular response to neurotransmitters and related vasoactive agents
General Pharmacology: The Vascular System, 1983 Constrictory and dilatory responses of pial arteries to various receptor stimulants and modulators were evaluated in vitro and compared in rat, rabbit, cat and man. For the constrictory response, differences were noted especially in the rabbit, which responded strongly to histamine but poorly to noradrenaline and prostaglandin F2 alpha. Histamine was a
Jan Erik Hardebo, John Hanko, Ch. Owman
openalex +3 more sources
The Journal of Pharmacology and Experimental Therapeutics, 1998 Isolated monkey cerebral arteries denuded of the endothelium responded to transmural electrical stimulation (5 Hz for 40 sec) with relaxations that are mediated by nitric oxide (NO) synthesized from L-arginine. The relaxant response was slightly inhibited by duroquinone, a superoxide anion-generating agent.
Tomio Okamura +3 more
openalex +3 more sources
Journal of Neurochemistry, 1976 Abstract— The effects of 121 mm‐K+, 10 mm‐glutamate, 5 mm‐GABA, 1 mm‐glycine, 0.1 mm‐NE, and 1–10 μmACh on cyclic GMP levels in tissue slices prepared from cerebral cortex and cerebellum of mouse, rabbit, guinea‐pig, cat, and rat were studied. Basal levels of cyclic GMP in the cerebella of mice, guinea‐pigs and cats were 4–15 and 70 pmol/mg prot in rat,
Dorothy A. Kinscherf +4 more
openalex +3 more sources