Results 181 to 190 of about 170,105 (313)

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

open access: yesIbrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Natural compounds as multitarget agents in Alzheimer's diseases: evidence from <i>in vivo</i> and <i>in vitro</i> models. [PDF]

open access: yesFront Pharmacol
Suswidiantoro V   +7 more
europepmc   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

open access: yesIbrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma   +3 more
wiley   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Effects from a single application of photobiomodulation on pain intensity from perineal trauma related to childbirth: A randomized controlled trial

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To analyze the effects of a single photobiomodulation (PBM) application on perineal pain and healing in women in the immediate postpartum period. Methods Randomized controlled trial, double‐blind, two‐center, with 60 postpartum women with perineal trauma and pain scoring 4 or more on the Numeric Rating Scale (NRS).
Edna Jéssica Lima Gondim   +5 more
wiley   +1 more source

Microbial metabolites in tumor epigenetic regulation

open access: yesiMeta, EarlyView.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang   +31 more
wiley   +1 more source

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