Results 241 to 250 of about 1,668,634 (294)

Neurotransmitter Interactions and Responsivity to Cholinomimetic Agents

1992
There is now overwhelming evidence for the involvement of forebrain cholinergic systems in Alzheimer’s disease and the cognitive processes that subserve learning and memory (Perry et al., 1978; Bigl et al., 1987; Koshimura et al., 1987; Doucette et al., 1986; Ichimiya et al., 1986; Saper et al., 1985;Whitehouse, 1986; McGeer et al., 1984; Mann et al ...
Vahram Haroutunian, K L Davis
exaly   +2 more sources

Discoveries of Neurotransmitter Agents and Modulators of Neuronal Functions

1992
At a dinner speech in Atlantic City in 1950, Otto Loewi commented on some facets of his work that had led to the discovery of neurochemical transmission. He mentioned that Sir Walter Fletcher, years after the discovery, reminded him that as far back as 1903 Loewi had pointed out to him the possibility of a neurochemical transmission.
exaly   +2 more sources

Glycine – an important neurotransmitter and cytoprotective agent

Acta Anaesthesiologica Scandinavica, 2005
Background:  Glycine, the simplest of the amino acids, is an essential component of important biological molecules, a key substance in many metabolic reactions, the major inhibitory neurotransmitter in the spinal cord and brain stem, and an anti‐inflammatory, cytoprotective, and immune modulating substance.Material and methods:  Based on available ...
R Y, Gundersen, P, Vaagenes, T, Breivik, F, Fonnum, P K, Opstad   +4 more
openaire   +2 more sources

Neurotoxic and Neurotrophic Effects of GABAergic Agents on Developing Neurotransmitter Systems

1998
Jean M Lauder
exaly   +2 more sources

Species variation in the cerebrovascular response to neurotransmitters and related vasoactive agents

General Pharmacology: The Vascular System, 1983
Constrictory and dilatory responses of pial arteries to various receptor stimulants and modulators were evaluated in vitro and compared in rat, rabbit, cat and man. For the constrictory response, differences were noted especially in the rabbit, which responded strongly to histamine but poorly to noradrenaline and prostaglandin F2 alpha. Histamine was a
J E, Hardebo, J, Hanko, C, Owman
openaire   +2 more sources

Using the neurotransmitter serotonin to target imaging agents to glioblastoma cells

Investigational New Drugs, 2012
The neurotransmitter serotonin is involved in numerous bodily functions via seven different serotonin receptor subfamilies. Serotonin plays a role in gastrointestinal functions like intestinal secretion or peristalsis and neuropsychiatric events like depression or migraine.
Sturzu, Alexander, Sheikh, Sumbla, Klose, Uwe, Echner, Hartmut, Kalbacher, Hubert, Deeg, Martin, Horger, Marius, Ernemann, Ulrike, Heckl, Stefan, Nägele, Thomas   +9 more
openaire   +3 more sources

A catecholamine neurotransmitter: epinephrine as a CO ₂ wet scrubbing agent

Chemical Communications, 2019
Adrenaline can be used to capture CO 2 when dissolved in DMSO.
Ala'a F. Eftaiha, Farah M. Mustafa, Fatima Alsoubani, Khaleel I. Assaf, Abdussalam K. Qaroush   +4 more
openaire   +2 more sources

Mesoporous, anisotropic nanostructures from bioinspired polymeric catecholamine neurotransmitters and their potential application as photoacoustic imaging agents

Journal of Materials Chemistry B, 2022
Different process parameters can be used to fabricate polydopamine, polynorepinephrine, and polyepinephrine nanospheres and mesoporous nanomaterials (golf balls and bowls) with structure-dependent performance as photoacoustic imaging agents.
Zhenzhen Lu, Shahinur Acter, Boon Mian Teo, Alexis I. Bishop, Rico F. Tabor, Mark Louis P. Vidallon   +5 more
openaire   +2 more sources

Effect of antidepressant agents on β-adrenergic receptor and neurotransmitter regulatory systems

Pharmacology Biochemistry and Behavior, 1980
Abstract The effects of established and several novel antidepressant agents on brain monoamine oxidase A and B; high affinity synaptosomal uptake of norepinephrine, dopamine and serotonin; and β-adrenergic receptor kinetics evaluated by (3H)-dihydroalprenolol binding to cortical membranes are described.
L R, Meyerson, H H, Ong, L L, Martin, D B, Ellis   +3 more
openaire   +2 more sources

Chemotherapeutic agents do not interact with neurotransmitter receptors

Cancer Chemotherapy and Pharmacology, 1987
The interactions of cisplatin, 5-fluorouracil, doxorubicin, mitomycin, carmustine (BCNU), cyclophosphamide, methotrexate and thio-TEPA were assessed at three neurotransmitter receptor binding sites. Each drug was inactive at concentrations as high as 10(-4) M in displacing the specific binding of 3H-spiperone to dopamine D2, 3H-pyrilamine to histamine ...
openaire   +2 more sources