Poly-arginine peptide R18D reduces neuroinflammation and functional deficits following traumatic brain injury in the Long-Evans rat [PDF]
We have previously demonstrated that the poly-arginine peptide R18 can improve histological and functional outcomes following traumatic brain injury (TBI) in the Sprague–Dawley rat.
Anderton, Ryan S +5 more
core +1 more source
The NOX2-ROS-NLRP3 inflammasome axis in traumatic brain injury
Background Phagocyte NADPH oxidase 2 (NOX2) is an enzyme complex responsible for reactive oxygen species (ROS) production. Chronic NOX2 activity sustains oxidative stress/damage and drives neuroinflammation following traumatic brain injury (TBI).
Janeen Laabei +11 more
doaj +1 more source
Differential detection of impact site versus rotational site injury by magnetic resonance imaging and microglial morphology in an unrestrained mild closed head injury model. [PDF]
Seventy-five percent of all traumatic brain injuries are mild and do not cause readily visible abnormalities on routine medical imaging making it difficult to predict which individuals will develop unwanted clinical sequelae. Microglia are brain-resident
Carson, Monica J +4 more
core
New Mechanics of Traumatic Brain Injury
The prediction and prevention of traumatic brain injury is a very important aspect of preventive medical science. This paper proposes a new coupled loading-rate hypothesis for the traumatic brain injury (TBI), which states that the main cause of the TBI ...
A Kadic +67 more
core +2 more sources
Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity. [PDF]
Mild traumatic brain injury (mTBI) disproportionately affects military service members and is very difficult to diagnose. To-date, there is currently no blood-based, diagnostic biomarker for mTBI cases with persistent post concussive symptoms. To examine
Baker, Dewleen G +12 more
core
Delayed hypoxemia after traumatic brain injury exacerbates long-term behavioral deficits [PDF]
Brody, David L +3 more
core +2 more sources
Background/Objectives: Blast-induced traumatic ocular injuries (bTOI) pose a significant risk to military and civilian populations, often leading to visual impairment or blindness.
Chetan Pundkar +5 more
doaj +1 more source
Free Neuropathology, Bd. 5 (2024)
David Priemer, Daniel P. Perl
openaire +3 more sources
Computerised tomography indices of raised intracranial pressure and traumatic brain injury severity in a New Zealand sample [PDF]
After traumatic brain injury (TBI) complex cellular and biochemical processes occur¹ including changes in blood flow and oxygenation of the brain; cerebral swelling; and raised intracranial pressure (ICP).² This can dramatically worsen the damage³ and ...
Barker-Collo, Suzanne +4 more
core +1 more source

