Results 31 to 40 of about 44,677 (196)

Cerebral Microvascular and Systemic Effects Following Intravenous Administration of the Perfluorocarbon Emulsion Perftoran

open access: yesJournal of Functional Biomaterials, 2016
Oxygen-carrying perfluorocarbon (PFC) fluids have the potential to increase tissue oxygenation during hypoxic states and to reduce ischemic cell death.
Rania Abutarboush   +10 more
doaj   +1 more source

Differential neuroproteomic and systems biology analysis of spinal cord injury [PDF]

open access: yes, 2016
Acute spinal cord injury (SCI) is a devastating condition with many consequences and no known effective treatment. Although it is quite easy to diagnose traumatic SCI, the assessment of injury severity and projection of disease progression or recovery ...
Bramlett, Helen M   +8 more
core   +2 more sources

Effects of the Oxygen-Carrying Solution OxyVita C on the Cerebral Microcirculation and Systemic Blood Pressures in Healthy Rats

open access: yesJournal of Functional Biomaterials, 2014
The use of hemoglobin-based oxygen carriers (HBOC) as oxygen delivering therapies during hypoxic states has been hindered by vasoconstrictive side effects caused by depletion of nitric oxide (NO).
Rania Abutarboush   +9 more
doaj   +1 more source

Optogenetic Interrogation of Circuits Following Neurotrauma

open access: yesFrontiers in Molecular Neuroscience, 2021
Biological and engineering strategies for neural repair and recovery from neurotrauma continue to emerge at a rapid pace. Until recently, studies of the impact of neurotrauma and repair strategies on the reorganization of the central nervous system have ...
Steven Ceto   +6 more
doaj   +1 more source

Genome-wide gene expression profiling of stress response in a spinal cord clip compression injury model. [PDF]

open access: yes, 2013
BackgroundThe aneurysm clip impact-compression model of spinal cord injury (SCI) is a standard injury model in animals that closely mimics the primary mechanism of most human injuries: acute impact and persisting compression.
Boutros, Paul C   +5 more
core   +3 more sources

Repeated Low-Level Blast Overpressure Leads to Endovascular Disruption and Alterations in TDP-43 and Piezo2 in a Rat Model of Blast TBI

open access: yesFrontiers in Neurology, 2019
Recent evidence linking repeated low-level blast overpressure exposure in operational and training environments with neurocognitive decline, neuroinflammation, and neurodegenerative processes has prompted concern over the cumulative deleterious effects ...
Lanier Heyburn   +12 more
doaj   +1 more source

Combining H-FABP and GFAP increases the capacity to differentiate between CT-positive and CT-negative patients with mild traumatic brain injury [PDF]

open access: yes, 2018
Mild traumatic brain injury (mTBI) patients may have trauma-induced brain lesions detectable using CT scans. However, most patients will be CT-negative. There is thus a need for an additional tool to detect patients at risk. Single blood biomarkers, such
Bustamante, Alejandro   +8 more
core   +1 more source

Duration of Posttraumatic Amnesia Predicts Neuropsychological and Global Outcome in Complicated Mild Traumatic Brain Injury. [PDF]

open access: yes, 2016
OBJECTIVES: Examine the effects of posttraumatic amnesia (PTA) duration on neuropsychological and global recovery from 1 to 6 months after complicated mild traumatic brain injury (cmTBI). PARTICIPANTS: A total of 330 persons with cmTBI defined as Glasgow
Barber, Jason   +10 more
core   +2 more sources

Neurotrauma: 2023 Update

open access: yesFree neuropathology, 2023
2022 was a productive year for research in traumatic brain injury (TBI) and resultant neuropathology. After an extensive review, we present related studies and publications which we felt were of particular importance to the neuropathology community. First, 2022 was highlighted by important advancements in the diagnosis and, moreover, our understanding ...
David Priemer, Daniel P. Perl
openaire   +3 more sources

Treatment of Swine Closed Head Injury with Perfluorocarbon NVX-428

open access: yesMedical Sciences, 2020
Pre-hospital treatment of traumatic brain injury (TBI) with co-existing polytrauma is complicated by requirements for intravenous fluid volume vs. hypotensive resuscitation.
Francoise Arnaud   +9 more
doaj   +1 more source

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