Results 81 to 90 of about 44,677 (196)

MPs-ACT, an Assay to Evaluate the Procoagulant Activity of Microparticles

Clinical and Applied Thrombosis/Hemostasis, 2023
The procoagulant effect of microparticles (MPs) contributes to hypercoagulability-induced thrombosis. We provide preliminary findings of the MPs-Activated Clotting Time (MPs-ACT) assay to determine the procoagulant activity of MPs.
Yalong Gao PhD, Xiaotian Li PhD, Yafei Qin MD, Jianlong Men PhD, Jing Ren PhD, Xiaochun Li MM, Chunlei Xu MD, Qifeng Li PhD, Ying Li PhD, Weiyun Cui MM, Shu Zhang PhD, Lei Li MM, Yaohua Li MD, Jianning Zhang MD, Li Liu PhD   +14 more
doaj   +1 more source

Association of Cerebral Oxygenation During Prehospital Anaesthesia and Functional Outcome: A Prospective, Observational Multi‐Centre Cohort Study of 1014 Patients

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 1, January 2026.
ABSTRACT Background Many patients undergoing prehospital anaesthesia may be at risk of inadequate cerebral oxygenation due to underlying conditions or adverse events like hypotension or hypoxia. This study examined whether a decrease in regional cerebral oxygen saturation (rSO2) measured with near‐infrared spectroscopy (NIRS) during prehospital ...
Anssi Saviluoto, Lasse Raatiniemi, Simo Mäkelä, Tuukka Toivonen, Piritta Setälä, Hetti Kirves, Miretta Tommila, Pamela Toivonen, Simo Tukia, Jouni Nurmi   +9 more
wiley   +1 more source

Prognostic value of early magnetic resonance imaging in dogs after traumatic brain injury: 50 cases [PDF]

, 2014
Retrospective study of dogs with TBI that underwent 1.5T MRI within 14 days after head trauma. MRI evaluators were blinded to the clinical presentation, and all images were scored based on an MRI grading system (Grade I [normal brain parenchyma] to Grade
Asikainen, Bazarian, Bigler, Brain Trauma Foundation, Byrne, Chew, Englander, Firsching, Frey, Friedenberg, Hicks, Hilario, Kearsley-Fleet, Klein, Kornegay, Lagares, Lannsjö, Lee, Lowenstein, Löscher, Management of Concussion/mTBI Working Group, McDonald, Mittl, Orrison, Pearl, Platt, Sande, Schwartz-Porsche, Shenton, Shores, Simpson, Skandsen, Steinmetz, Tanoue, Vespa, Wendt-Hornickle, Wilde, Yuh, Zuercher   +38 more
core   +2 more sources

Comparison of automated and manual approaches for microglial quantification and classification: A focus on the HALO digital pathology platform

Brain Pathology, Volume 36, Issue 1, January 2026.
The Halo microglial activation module has not been formally validated in the literature. Comparison of this module with established methods revealed varied performance dependent on tissue thickness, highlighting the need for care to be taken when optimising image analysis parameters. Abstract Phenotypic changes in microglia have been linked to multiple
Laura M. Carr, Bianca Guglietti, Ing Chee Wee, Ian F. Musgrave, Sanam Mustafa, Frances Corrigan, Lyndsey E. Collins‐Praino   +6 more
wiley   +1 more source

Improving the care of people with traumatic brain injury through the Neurotrauma Evidence Translation (NET) program: protocol for a program of research

Implementation Science, 2012
The Neurotrauma Evidence Translation (NET) program was funded in 2009 to increase the uptake of research evidence in the clinical care of patients who have sustained traumatic brain injury.
Green Sally E, Bosch Marije, McKenzie Joanne E, O’Connor Denise A, Tavender Emma J, Bragge Peter, Chau Marisa, Pitt Veronica, Rosenfeld Jeffrey V, Gruen Russell L   +9 more
doaj   +1 more source

Mesenteric Vascular Dysregulation and Intestinal Inflammation Accompanies Experimental Spinal Cord Injury

, 2016
Cervical and high thoracic spinal cord injury (SCI) drastically impairs autonomic nervous system function. Individuals with SCI at thoracic spinal-level 5 (T5) or higher often present cardiovascular disorders that include resting systemic arterial ...
Besecker, Emily Swartz, Cooper, Timothy K., Deiter, Gina M., Holmes, Gregory Michael, Pironi, Nicole   +4 more
core   +1 more source

Unveiling the Proteomic Landscape of Extracellular Vesicles: Implications for Neurodegeneration and Neuroprotection

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Extracellular vesicles (EVs) are tiny, membrane‐covered packets that cells naturally release to send molecular information to one another. In the brain, they function as couriers that move proteins, lipids, and other signals between neurons, glial cells, and the blood–brain barrier.
Berenice N. Bernal‐Vicente, Isaac Ponce, Emmanuel Ríos‐Castro, Perla Moreno‐Castilla, Luis B. Tovar‐y‐Romo   +4 more
wiley   +1 more source

modCHIMERA: A novel murine closed-head model of moderate traumatic brain injury [PDF]

, 2018
Traumatic brain injury is a major source of global disability and mortality. Preclinical TBI models are a crucial component of therapeutic investigation.
Bayly, P. V., Brody, D. L., Fanizzi, C., Gangolli, M., Kim, J. H., Kummer, T. T., Sauerbeck, A. D., Wellington, C. L.   +7 more
core   +2 more sources

Advancing Trauma Systems in the United States: Bridging Disparities Through State‐Level Legislation and a Health Systems Approach

Health Services Research, Volume 61, Issue 1, February 2026.
Bilal Irfan, Zain Hashmi, Tatiana Ramos, Molly Jarman   +3 more
wiley   +1 more source

Precision Diagnostics in Sports‐Related Traumatic Brain Injury: Pathophysiology, Biomarker Development and Emerging Technologies

Advanced Sensor Research, Volume 4, Issue 12, December 2025.
Sports‐related traumatic brain injuries (TBIs) remain underdiagnosed, within amateur athletic cohorts. This review critically synthesises recent advancements in AI‐assisted neuroimaging, blood‐based biomarker profiling, wearable biosensing platforms for early detection, injury stratification, and longitudinal surveillance of TBIs.
Daniel Nicol, Mohamed T. Patel, Debarati Bhowmik, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source