Results 261 to 270 of about 189,919 (333)

Specifically Breaking Through the Injured Blood‐Brain Barrier With Tannic Acid‐Based Nanomedicine for Ischemic Stroke Ischemia Reperfusion Treatment

Exploration, EarlyView.
Protecting neuronal mitochondria by eliminating the mitochondrial ROS (mtROS) storm is crucial to abrogate the neuronal damage cascade of ischemic stroke ischemia reperfusion (ISIR), which is a long‐standing challenge in the field of ischemic stroke (IS).
Xiaojing Shi, Shuya Wang, Tingli Xiong, Ruishi Li, Wenxuan Zheng, Wensheng Chen, Tianjiao Zhao, Yongqi Yang, Xiaohong Ying, Weimin Qi, Yingci Xia, Jue Wang, Yuqi Zhang, Qiong Huang, Yayun Nan, Kelong Ai   +15 more
wiley   +1 more source

Dexmedetomidine administration as a possible cognitive enhancer through increasing the level of brain-derived neurotrophic factors in surgical patients: a systematic review and meta-analysis. [PDF]

BMC Anesthesiol
Dehbozorgi M, Fereidooni F, Bozorgmehr R, Bagherpour JZ, Shafiee A, Mohammadi I, Amini MJ, Seighali N, Jafarabady K, Rajai Firouzabadi S, Akbarzade D, Bahri RA.   +11 more
europepmc   +1 more source

Neurotrophic Factor Derived Invasion of Pancreatic Cancer.

, 1998
Yuji Okada, Hiromitsu Takeyama, Mikinori Sato, Tadao Manabe   +3 more
openalex   +2 more sources

Nobiletin Ameliorates Aβ1–42‐Induced Cognitive Disorder and Mitochondrial Dysfunction via Targeting the Key Circadian Regulator Bmal1

Food Safety and Health, EarlyView.
Nobiletin (NOB) ameliorates Aβ‐induced Alzheimer’s pathology by restoring circadian rhythm via Bmal1. NOB rescues cognitive deficits, synaptic damage, and mitochondrial dysfunction in mice and neurons by enhancing Bmal1/Clock oscillations and downstream mitochondrial integrity, positioning circadian regulation as a therapeutic target for Alzheimer's ...
Huajing Gao, Qinglin Qu, Ning Wang, Xue Gao, Peihua Li, Yanquan Mou, Xiangrui Kong, Yannan Chen, Dapeng Li, Xintong Tan   +9 more
wiley   +1 more source

A novel probiotic formula, BLLL, ameliorates chronic stress-induced depression-like behaviors in mice by reducing neuroinflammation and increasing neurotrophic factors. [PDF]

Front Pharmacol
Ye M, Ji F, Huang C, Li F, Zhang C, Zhang Y, Wang R, Ma K, Lu X, Wang H.   +9 more
europepmc   +1 more source

Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N -methyl- d -aspartic acid receptor activity

, 1998
Eric S. Levine, Robert A. Crozier, Ira B. Black, Mark R. Plummer   +3 more
openalex   +1 more source

AAV‐Based Intracerebral Administration of BDNF Promotes Myelin Repair and Cognitive Improvement After Cuprizone‐Induced Demyelination

Glia, EarlyView.
AAV‐BDNF improves cognitive performance after cuprizone‐induced de‐myelination. BDNF promotes OPC maturation and enhances remyelination in the corpus callosum. Mitochondrial integrity is preserved through reduced swelling and improved morphology. ABSTRACT Multiple sclerosis (MS) is a chronic neurological disorder involving immune‐mediated demyelination
Yousra El Ouaamari, Leonardo Ricciardi, Sanne van der Heijden, Antonia Peter, Jorrit De Waele, Jasper Van den Bos, Debby Van Dam, Elke Calus, Sarah Kuhn, Waleed Marei, Yvonne Dombrowski, Marleen Verhoye, Peter Ponsaerts, Inez Wens, Nathalie Cools   +14 more
wiley   +1 more source

Association of Neurotrophic Factors at Midlife With In Vivo Measures of β-Amyloid and Tau Burden 15 Years Later in Dementia-Free Adults. [PDF]

Neurology
Weinstein G, Kojis DJ, Ghosh S, Beiser AS, Seshadri S.   +4 more
europepmc   +1 more source

Building Immunocompetent Cerebral Organoids From a Developmental Perspective

Glia, EarlyView.
Conventional cerebral organoids do not contain microglia, which must be added. We propose recommendations to assess microglial immunocompetence using quantitative approaches and stringent statistical analysis to help develop standardized protocols. ABSTRACT Cerebral organoids derived from human induced pluripotent stem cells (iPSCs) are increasingly ...
Xabier Cuesta‐Puente, Marco Gonzalez‐Dominguez, Marta Pereira‐Iglesias, Nerea Perez‐Arriazu, Patricia Villegas‐Zafra, Paula Ramos‐Gonzalez, Fabio Cavaliere, Nora Bengoa‐Vergniory, Amanda Sierra   +8 more
wiley   +1 more source

The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance

Glia, EarlyView.
Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis, Vishwanath V. Prabhu, Bruce D. Carter   +2 more
wiley   +1 more source