Results 281 to 290 of about 12,820,523 (360)

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Editorial: The legacy of Dr. Rita Levi-Montalcini: advances in neurotrophic factors in brain disease development and treatment. [PDF]

Front Mol Neurosci
Chen WJ, Kung WM, Lin MS.
europepmc   +1 more source

Neurotrophic factors in combinatorial approaches for spinal cord regeneration

Cell and Tissue Research, 2012
J. McCall, N. Weidner, A. Blesch
semanticscholar   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

The effect of salidroside in promoting endogenous neural regeneration after cerebral ischemia/reperfusion involves notch signaling pathway and neurotrophic factors. [PDF]

BMC Complement Med Ther
Zheng J, Zhang J, Han J, Zhao Z, Lin K.
europepmc   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Dexmedetomidine administration as a possible cognitive enhancer through increasing the level of brain-derived neurotrophic factors in surgical patients: a systematic review and meta-analysis. [PDF]

BMC Anesthesiol
Dehbozorgi M, Fereidooni F, Bozorgmehr R, Bagherpour JZ, Shafiee A, Mohammadi I, Amini MJ, Seighali N, Jafarabady K, Rajai Firouzabadi S, Akbarzade D, Bahri RA.   +11 more
europepmc   +1 more source

A set of serum proteomic biomarkers differentiates celiac children from age and human leukocyte antigen‐matched healthy controls

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective The latest European Society of Gastroenterology Hepatology and Nutrition (ESPGHAN) criteria for celiac disease (CD) diagnosis reduced the requirement for a small intestinal biopsy but still, for most of the cases a small intestinal biopsy is required for a safe diagnosis: hence the attempt to identify serum biomarkers that could ...
Roberta Mandile, Michele Francesco di Tolla, Martina Carpinelli, Janneke Nicoline Samsom, Rossella De Cegli, Maria Vittoria Barone, Riccardo Troncone, Pietro Formisano, Luigi Greco, Renata Auricchio   +9 more
wiley   +1 more source

Longan flower water extract promotes sleep in mice via the serotonin–melatonin axis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Longan (Dimocarpus longan) flower is an underutilized botanical byproduct rich in polyphenols with reported neuroprotective actions, yet its role in sleep regulation remains unclear. This study aimed to evaluate the sleep‐promoting effects of longan flower water extract (LFWE) and its underlying neurochemical mechanisms in vivo ...
Tzu‐Huan Hung, Chiu‐Ping Cheng, Wei‐Chung Chiou, Tzu‐Lan Hsia, Hui‐Kang Liu, Hsu‐Feng Lu, Yu‐Heng Lai, Shang‐Ting Tsai, Chiung‐Ju Chen, Cheng Huang   +9 more
wiley   +1 more source