Results 101 to 110 of about 1,885 (233)
Molecular Nutrition &Food Research, EarlyView.Paired peripheral‐blood RNA‐seq from MiBLEND was deconvolved with CIBERSORTx to profile leukocyte composition and cell‐type‐specific transcriptomic responses to seven fruit‐and‐vegetable blends. Deconvolution yielded 22 leukocyte subtypes that correlated with laboratory WBC reports (R = 0.886, p ≤ 0.01).
Yueqin He +3 more
wiley +1 more source
Cell Transplantation, 2007 We present an insight of the effects of combination therapy with neurotrophin-3 and neural stem cell on functional recovery after spinal cord injury (SCI).
Luyi Zhang +3 more
doaj +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
Neuroprotection, EarlyView.This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Sympathetic neurons in neonatal rats require endogenous neurotrophin-3 for survival [PDF]
, 1995 Xin‐Fu Zhou, Ryan B. Rush
openalex +1 more source
Neuroprotection, EarlyView.Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal +2 more
wiley +1 more source
Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Age‐related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD) are an increasing public health concern. Whereas the pathology of these diseases is complex, chronic central inflammation, or neuroinflammation, is commonly observed across many neurodegenerative diseases ...
Alex Foster‐Powell +4 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT To support the benefit–risk assessment and dose justification of repotrectinib for patients with c‐ros oncogene 1 (ROS1) positive non‐small cell lung cancer (NSCLC) or neurotrophin receptor tyrosine kinase (NTRK)‐positive solid tumors, exposure–response analyses were conducted.
Shengnan Du +8 more
wiley +1 more source
Differential expression of neurotrophins in postnatal C57BL/6 mice striatum
International Journal of Biological Sciences, 2009 Neurotrophin expression in early stages of development is crucial for brain assembly and function. In particular, postnatal expression of neurotrophins has not been well documented in the neostriatum and in general neurotrophins or their receptor mRNA's ...
V. Zermeño, S. Espindola, E. Mendoza, E. Hernández-Echeagaray
doaj
Conductive Materials and Electrical Stimulation for Auditory Restoration
Sensory Neuroscience, EarlyView.Applications of electroconductive biomaterials and electrical stimulation in cochlear tissue engineering.(1) Enable auditory neural repair through conductive materials and electrical stimulation, enhancing neuron survival and synaptic plasticity.(2) Integrate optogenetic‐electrical systems and cochlear organoid platforms for frequency‐specific ...
Menghui Liao +8 more
wiley +1 more source
Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury
Small Science, EarlyView.Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li +5 more
wiley +1 more source