Results 101 to 110 of about 16,647,982 (293)

Leukemia Inhibitory Factor Augments Neurotrophin Expression and Corticospinal Axon Growth after Adult CNS Injury [PDF]

open access: yes, 1999
The cytokine leukemia inhibitory factor (LIF) modulates glial and neuronal function in development and after peripheral nerve injury, but little is known regarding its role in the injured adult CNS.
Blesch, A.   +5 more
core   +1 more source

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk   +7 more
wiley   +1 more source

Nanoparticles in the treatment of chronic lung diseases [PDF]

open access: yes, 2019
Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G   +9 more
core   +2 more sources

Non‐Invasive Brain Stimulation in Chronic Pain: Current Evidence, Network Perspectives and Paths to Personalization

open access: yesSensory Neuroscience, EarlyView.
Chronic pain reflects maladaptive network interactions across sensory, salience/affective, and descending modulatory pathways. We review evidence for non‐invasive brain stimulation—rTMS, tES, and low‐intensity focused ultrasound—highlighting modest, variable, and often short‐lived analgesic effects under conventional protocols.
Fabian Broecker, Sven Vanneste
wiley   +1 more source

Emergence of functional sensory subtypes as defined by transient receptor potential channel expression [PDF]

open access: yes, 2007
The existence of heterogeneous populations of dorsal root ganglion (DRG) neurons conveying different somatosensory information is the basis for the perception of touch, temperature, and pain. A differential expression of transient receptor potential (TRP)
AlQatari, M   +3 more
core   +1 more source

The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation

open access: yesAndrology, EarlyView.
Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani   +6 more
wiley   +1 more source

TrkC Overexpression Enhances Survival and Migration of Neural Stem Cell Transplants in the Rat Spinal Cord

open access: yesCell Transplantation, 2002
Although CNS axons have the capacity to regenerate after spinal cord injury when provided with a permissive substrate, the lack of appropriate synaptic target sites for regenerating fibers may limit restoration of spinal circuitry.
Daniel A. Castellanos   +5 more
doaj   +1 more source

Neurotrophin-3 and Brain-Derived Neurotrophic Factor Induce Oligodendrocyte Proliferation and Myelination of Regenerating Axons in the Contused Adult Rat Spinal Cord

open access: yesJournal of Neuroscience, 1998
Functional loss after spinal cord injury (SCI) is caused, in part, by demyelination of axons surviving the trauma. Neurotrophins have been shown to induce oligodendrogliagenesis in vitro, but stimulation of oligodendrocyte proliferation and myelination ...
D. McTigue   +3 more
semanticscholar   +1 more source

Inducers of epithelial mesenchymal transition and cancer stem cells in malignant pleural effusions [PDF]

open access: yes, 2016
The Epithelial to Mesenchymal Transition (EMT) plays a role not only in tumor metastasis but also in tumor recurrence. This process is believed to be tightly linked to the presence of Cancer Stem Cells (CSCs) however, it is still not clear which ...
Cherubini, Emanuela   +5 more
core   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

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