Results 171 to 180 of about 83,880 (296)

Transphosphorylation of the Neurotrophin Trk Receptors [PDF]

open access: hybrid, 1996
Marco Canossa   +2 more
openalex   +1 more source

Comparative mapping of single‐cell transcriptomic landscapes in neurodegenerative diseases

open access: yesAlzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and Parkinson's disease (PD) represent a spectrum of neurodegenerative diseases (NDDs). Here, we performed the first direct comparison of their transcriptomic landscapes.
E. Keats Shwab   +9 more
wiley   +1 more source

Antisense oligonucleotides directed against App and Rab5 normalized endosomal Rab activity and reversed DS‐AD‐linked degenerative phenotypes in the Dp16 mouse model of Down syndrome

open access: yesAlzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION Down syndrome (DS) markedly raises the risk of Alzheimer's disease (DS‐AD). Our findings identified widespread dysregulation of the endolysosomal network (ELN) in DS and DS‐AD brains, driven by increased APP gene dose, hyperactivation of RAB5, and elevated levels of guanine nucleotide exchange factors (GEFs) for RABs 7 and 11 ...
Xu‐Qiao Chen   +12 more
wiley   +1 more source

Drug Targets in Neurotrophin Signaling in the Central and Peripheral Nervous System

open access: yesMolecular Neurobiology, 2018
M. Kashyap   +3 more
semanticscholar   +1 more source

Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3.

open access: green, 1991
Beat Knüsel   +6 more
openalex   +1 more source

Neurotrophin 4 Is Required for the Survival of a Subclass of Hair Follicle Receptors [PDF]

open access: bronze, 1998
Cheryl L. Stucky   +4 more
openalex   +1 more source

Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity. [PDF]

open access: yes, 2015
Cancer stem cells (CSCs) are considered to be the cause of tumor initiation, metastasis and recurrence. Additionally, CSCs are responsible for the failure of chemotherapy and radiotherapy.
Chen, Xinfeng   +12 more
core  

The Causal Relationship Between Neurotrophic Factors and Delirium: A Mendelian Randomization Study

open access: yesBrain and Behavior, Volume 15, Issue 5, May 2025.
Overview of MR analysis. SNPs: single nucleotide polymorphisms; inverse‐variance weighted (IVW); weighted median (WM); leave‐one‐out (LOO); glial cell‐derived neurotrophic factor (GDNF); ciliary neurotrophic factor (CNTF); brain‐derived neurotrophic factor (BDNF); nerve growth factor (NGF); neurotrophin‐3 (NT‐3); neurotrophin‐4 (NT‐4); brain‐derived ...
Han Wu   +3 more
wiley   +1 more source

Estrogen-Induced Activation of Mitogen-Activated Protein Kinase in Cerebral Cortical Explants: Convergence of Estrogen and Neurotrophin Signaling Pathways [PDF]

open access: hybrid, 1999
Meharvan Singh   +4 more
openalex   +1 more source

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