Transphosphorylation of the Neurotrophin Trk Receptors [PDF]
Marco Canossa+2 more
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Comparative mapping of single‐cell transcriptomic landscapes in neurodegenerative diseases
Abstract INTRODUCTION Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and Parkinson's disease (PD) represent a spectrum of neurodegenerative diseases (NDDs). Here, we performed the first direct comparison of their transcriptomic landscapes.
E. Keats Shwab+9 more
wiley +1 more source
Sympathetic neurons in neonatal rats require endogenous neurotrophin-3 for survival [PDF]
Xin‐Fu Zhou, Ryan B. Rush
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Abstract INTRODUCTION Down syndrome (DS) markedly raises the risk of Alzheimer's disease (DS‐AD). Our findings identified widespread dysregulation of the endolysosomal network (ELN) in DS and DS‐AD brains, driven by increased APP gene dose, hyperactivation of RAB5, and elevated levels of guanine nucleotide exchange factors (GEFs) for RABs 7 and 11 ...
Xu‐Qiao Chen+12 more
wiley +1 more source
Drug Targets in Neurotrophin Signaling in the Central and Peripheral Nervous System
M. Kashyap+3 more
semanticscholar +1 more source
Neurotrophin 4 Is Required for the Survival of a Subclass of Hair Follicle Receptors [PDF]
Cheryl L. Stucky+4 more
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Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity. [PDF]
Cancer stem cells (CSCs) are considered to be the cause of tumor initiation, metastasis and recurrence. Additionally, CSCs are responsible for the failure of chemotherapy and radiotherapy.
Chen, Xinfeng+12 more
core
The Causal Relationship Between Neurotrophic Factors and Delirium: A Mendelian Randomization Study
Overview of MR analysis. SNPs: single nucleotide polymorphisms; inverse‐variance weighted (IVW); weighted median (WM); leave‐one‐out (LOO); glial cell‐derived neurotrophic factor (GDNF); ciliary neurotrophic factor (CNTF); brain‐derived neurotrophic factor (BDNF); nerve growth factor (NGF); neurotrophin‐3 (NT‐3); neurotrophin‐4 (NT‐4); brain‐derived ...
Han Wu+3 more
wiley +1 more source
Estrogen-Induced Activation of Mitogen-Activated Protein Kinase in Cerebral Cortical Explants: Convergence of Estrogen and Neurotrophin Signaling Pathways [PDF]
Meharvan Singh+4 more
openalex +1 more source