The Impact of Intermittent Fasting on Brain-Derived Neurotrophic Factor, Neurotrophin 3, and Rat Behavior in a Rat Model of Type 2 Diabetes Mellitus [PDF]
Brain Sciences, 2021 Type 2 diabetes mellitus (T2DM) is known to be associated with an increased risk of dementia, specifically Alzheimer’s disease and vascular dementia. Intermittent fasting (IF) has been proposed to produce neuroprotective effects through the activation of
Basem H. Elesawy +4 more
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Neuroprotective effects of Neurotrophin-3 in MPTP-induced zebrafish Parkinson’s disease model [PDF]
Frontiers in Pharmacology, 2023 Introduction: Neurotrophin-3 (NT3) is a neuroprotective growth factor that induces the development, maintenance and survival of neurons. This study aims to localize NT3-expressing cells in the adult zebrafish brain and examine the role of NT3 in a ...
Noor Azzizah Omar +3 more
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The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection. [PDF]
PLoS Pathogens, 2015 The neurotrophic tyrosine kinase receptor type 2 (Ntrk2, also known as TrkB) and its ligands brain derived neurotrophic factor (Bdnf), neurotrophin-4 (NT-4/5), and neurotrophin-3 (NT-3) are known primarily for their multiple effects on neuronal ...
Jane E Dalton +6 more
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Neurotrophin-3–enhanced Nerve Regeneration Selectively Improves Recovery of Muscle Fibers Expressing Myosin Heavy Chains 2b [PDF]
, 1997 The purpose of this study was to evaluate the effect of neurotrophin 3 (NT-3) enhanced nerve regeneration on the reinnervation of a target muscle. Muscle fibers can be classified according to their mechanical properties and myosin heavy chain (MHC ...
G.D. Sterne +4 more
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Neurotrophin-3 accelerates reendothelialization through inducing EPC mobilization and homing [PDF]
Open Life Sciences, 2020 Rapid endothelialization is an effective way to treat intimal hyperplasia after intravascular stent implantation. Blood vessels and nerves coordinate with each other in function, while neurotrophin-3 (NT-3) is an important class of nerve growth factors ...
Chen Yan +3 more
doaj +2 more sources
A radiolabeled drug tracing method to study neurotrophin-3 retention and distribution in the cochlea after nano-based local delivery [PDF]
MethodsX, 2020 Hearing loss is the most common sensory deficit worldwide with no approved therapeutics for treatment. Local neurotrophin delivery into the cochlea has shown great potential in protecting and repairing the sensory cells important for hearing.
Patrick Lam +7 more
doaj +2 more sources
Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells [PDF]
Frontiers in Immunology, 2017 Plasmacytoid dendritic cells (pDCs) regulate innate and adaptive immunity. Neurotrophins and their receptors control the function of neuronal tissue. In addition, they have been demonstrated to be part of the immune response but little is known about the
Joanna Bandoła +19 more
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Intervention effects of Ganoderma lucidum spores on epileptiform discharge hippocampal neurons and expression of Neurotrophin-4 and N-Cadherin [PDF]
, 2013 Epilepsy can cause cerebral transient dysfunctions. Ganoderma lucidum spores (GLS), a traditional Chinese medicinal herb, has shown some antiepileptic effects in our previous studies.
AA Ardelt +51 more
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Исследования и практика в медицине, 2023 Objective. Studying the levels of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF-β), and neurotrophin 3 (NT3) in the cerebral cortex and subcortical substance of female rats in an experimental model of extracerebral growth of ...
E. I. Surikova +10 more
doaj +1 more source
Improving Control of Gene Therapy-Based Neurotrophin Delivery for Inner Ear Applications
Frontiers in Bioengineering and Biotechnology, 2022 Background: Survival and integrity of the spiral ganglion is vital for hearing in background noise and for optimal functioning of cochlear implants. Numerous studies have demonstrated that supplementation of supraphysiologic levels of the neurotrophins ...
Madeleine St. Peter +7 more
doaj +1 more source