Neurotrophin-3 improves fracture healing in rats.
European review for medical and pharmacological sciences, 2018 This study aimed at investigating the role of Neurotrophin-3 (NT-3) in the bone fracture healing of rats and to provide a reference for clinical treatment.40 Sprague-Dawley (SD) rats were randomly divided into control group and NT-3 group. The tibia fracture model was made in NT-3 group, and the tibia bone mineral density (BMD) was measured before and ...
Wu Xy, Yang Li, Sun Dc, Xianfeng Li
openaire +3 more sources
Glia Preserve Their Own Functions While Compensating for Neighboring Glial Cell Dysfunction
Glia, EarlyView.When cortex glia lose their interactions with neuronal cell bodies, all neighboring glia infiltrate the region to clear extra neuronal corpses. Even while compensating for nearby glial dysfunction, glia maintain their own phagocytic functions. ABSTRACT Glial cells are essential for nervous system development, homeostasis, and disease response, engaging
Allison N. Beachum +13 more
wiley +1 more source
Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine [PDF]
, 1994 Mathew T. Martin‐Iverson +2 more
openalex +1 more source
Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis
Glia, EarlyView.OECs are similar to satellite glial cells. OECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. OECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs) envelope ...
Katja Senf +3 more
wiley +1 more source
Presence of Functional Neurotrophin TrkB Receptors in the Rat Superior Cervical Ganglion
Frontiers in Physiology, 2017 Sympathetic neurons express the neurotrophin receptors TrkA, p75NTR, and a non-functional truncated TrkB isoform (TrkB-Tc), but are not thought to express a functional full-length TrkB receptor (TrkB-Fl).
Pablo Valle-Leija +8 more
doaj +1 more source
Purification and characterisation of a brain‐derived neurotrophic factor/ neurotrophin‐3 (BDNF/NT‐3) heterodimer [PDF]
, 1994 Stefan Jungbluth +2 more
openalex +1 more source
Head &Neck, EarlyView.ABSTRACT Background The NTRK fusion gene is detected in most salivary gland secretory carcinomas. While tropomyosin receptor kinase (TRK) inhibitors are used for various solid tumors with the fusion gene, there are no reports regarding TRK inhibitor use for unresectable parotid gland carcinomas that subsequently shrink and become resectable.
Arisa Nagano +11 more
wiley +1 more source
The p75 neurotrophin receptor: at the crossroad of neural repair and death
Neural Regeneration Research, 2015 The strong repair and pro-survival functions of neurotrophins at their primary receptors, TrkA, TrkB and TrkC, have made them attractive candidates for treatment of nervous system injury and disease. However, difficulties with the clinical implementation
Rick B Meeker, Kimberly S Williams
doaj +1 more source
Retraction Notice to: Neurotrophin 3 Transduction Augments Remyelinating and Immunomodulatory Capacity of Neural Stem Cells. [PDF]
Mol Ther, 2023 Yang J +8 more
europepmc +1 more source
Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou +6 more
wiley +1 more source