Stroke Recovery in Rats after 24-Hour-Delayed Intramuscular Neurotrophin-3 Infusion. [PDF]
Duricki DA +12 more
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Delayed peripheral treatment with neurotrophin-3 improves sensorimotor recovery after central nervous system injury. [PDF]
Kakanos SG, Moon LDF.
europepmc +1 more source
Neurotrophin-3 restores synaptic plasticity in the striatum of a mouse model of Huntington's disease. [PDF]
Gómez-Pineda VG +3 more
europepmc +1 more source
Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats. [PDF]
Su YW +18 more
europepmc +1 more source
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Neurotrophin-3 Improves Functional Constipation
American Journal of Gastroenterology, 2003Neurotrophin-3 (NT-3) is a neurotrophic factor involved in the growth, development, and function of the nervous system. In preliminary studies, s.c. recombinant methionyl-human NT-3 enhanced transit throughout the GI tract and increased stool frequency in normal and constipated subjects.
Henry P, Parkman +11 more
openaire +3 more sources
Neurotrophin-3 and neurotrophin-4: The unsung heroes that lies behind the meninges
Neuropeptides, 2022Neurotrophin is a growth factor that regulates the development and repair of the nervous system. From all factors, two pioneer groups, the nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF), have been widely explored for their role in disease pathogenesis and potential use as therapeutic agents. Nonetheless, neurotrophin-3 (NT3) and
Noor Azzizah, Omar +2 more
openaire +2 more sources
Schizophrenia and neurotrophin‐3 alleles
Acta Psychiatrica Scandinavica, 1997Studies of brain anatomy and premorbid functioning indicate that schizophrenia may be of neurodevelopmental origin. In the neurotrophic factor neurotrophin‐3 (NT‐3) gene, the A3/147‐bp allele in a dinucleotide repeat polymorphism located in the promoter region was found to be associated with schizophrenia in a Japanese study. Another NT‐3 polymorphism (
E, Jŏnsson +6 more
openaire +2 more sources
Neurotrophin-3 and neurotrophin receptor immunoreactivity in peptidergic enteric neurons
Peptides, 2000In the rat small intestine, neurotrophin-3 immunoreactivity was identified in ganglion cells and in processes mostly innervating the mucosa and occasionally the muscle layer and vasculature. The vast majority of neurotrophin-3 immunoreactive neurons contained vasoactive intestinal polypeptide (VIP), but not substance P or related tachykinin (SP/TK ...
DE GIORGIO, Roberto +3 more
openaire +3 more sources
Monoclonal Antibodies against Human Neurotrophin-3
Biochemical and Biophysical Research Communications, 1993Hybridomas producing monoclonal antibodies (MoAbs) against human neurotrophin-3 (hNT-3) were established using recombinant hNT-3 produced in CHO cells and E. coli as immunogens. Of the five MoAbs obtained, MoAb 3w3 showed the highest antibody titer and also best neutralized NT-3 activity as measured by the survival of chick embryonic day-8 dorsal root ...
A, Shintani +6 more
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NEUROTROPHIN‐3 EXPRESSION IN HUMAN PANCREATIC CANCERS
The Journal of Pathology, 1997Some neurotrophic factors stimulate process outgrowth in peripheral and/or central nerve fibres. There is no published report that has focused on the expression of neurotrophic factors in human pancreatic cancer except basic fibroblast growth factor.
T, Ohta +11 more
openaire +2 more sources

