Results 261 to 270 of about 58,019 (320)
This study examined the impact of confounding factors on gene expression in postmortem brain tissue from individuals with psychiatric disorders. The expression was significantly associated with factors such as pH, RIN, PMI, and storage duration, highlighting the importance of accounting for these variables when interpreting transcriptomic data ...
Masataka Hatano+10 more
wiley +1 more source
and Analysis of Neurotrophin‐3 Activation of Arf6 and Rac‐1
Pedro F. Esteban+4 more
openalex +2 more sources
Conductive Nerve Conduits With Orientated Topological Structures From Ice‐Templating Technology
Conductive nerve conduits featuring oriented topological structures are engineered through ice‐templating technology, utilizing hydrogels and temperature gradients. Such conduits enhance peripheral nerve regeneration by integrating conductivity, aligned architecture, and growth factors, as demonstrated by improved motor recovery in rat models with ...
Hui Zhang+6 more
wiley +1 more source
ABSTRACT Chronic nicotine administration leads to neuroadaptations, an important process in nicotine and tobacco dependence for which treatments are limited. The cysteine pro‐drug, N‐acetyl‐cysteine (NAC), is a promising glutamatergic agent that has shown some clinical efficacy in reducing nicotine use in humans.
Kelsey Stoddart+5 more
wiley +1 more source
Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2. [PDF]
Patar A, Dockery P, McMahon S, Howard L.
europepmc +1 more source
The effects of tobacco alkaloids: anatabine, anabasine, and nicotine, were investigated in a model of mitochondrial stress, mimicking cellular pathology accompanying Parkinson's disease development. The alkaloids modulated mitochondrial function and alleviated the hallmarks of mitochondrial stress. However, they acted via slightly different mechanisms.
Dominika Malińska+11 more
wiley +1 more source
The Microbiota‐Gut‐Brain Connection: A New Horizon in Neurological and Neuropsychiatric Disorders
The microbiota‐gut‐brain axis (MGBA) is a crucial regulator of neurological and neuropsychiatric disorders, with gut microbiota dysbiosis linked to various diseases. Gut microbiota changes can lead to neurodegenerative diseases like depression, autism, schizophrenia, Parkinson's, Alzheimer's, dementia, multiple sclerosis, epilepsy, anxiety, and autism ...
Md. Faysal+12 more
wiley +1 more source
A close relationship exists between Cx43‐mediated gap junction channels in astrocytes and depression. The astrocytic network formed through gap junction channels, in collaboration with neurons, participates in mediating intercellular electrochemical signaling within the nervous system.
Hongbin Wang+11 more
wiley +1 more source