Results 261 to 270 of about 58,019 (320)

Impact of Confounding Factors in Human Postmortem Brain Tissues on Gene Expression Profiles: A Comparison of Patients With Schizophrenia, Bipolar Disorder, and Nonpsychiatric Controls

open access: yesNeuropsychopharmacology Reports, Volume 45, Issue 3, September 2025.
This study examined the impact of confounding factors on gene expression in postmortem brain tissue from individuals with psychiatric disorders. The expression was significantly associated with factors such as pH, RIN, PMI, and storage duration, highlighting the importance of accounting for these variables when interpreting transcriptomic data ...
Masataka Hatano   +10 more
wiley   +1 more source

and Analysis of Neurotrophin‐3 Activation of Arf6 and Rac‐1

open access: green, 2008
Pedro F. Esteban   +4 more
openalex   +2 more sources

Conductive Nerve Conduits With Orientated Topological Structures From Ice‐Templating Technology

open access: yesSmart Medicine, Volume 4, Issue 3, September 2025.
Conductive nerve conduits featuring oriented topological structures are engineered through ice‐templating technology, utilizing hydrogels and temperature gradients. Such conduits enhance peripheral nerve regeneration by integrating conductivity, aligned architecture, and growth factors, as demonstrated by improved motor recovery in rat models with ...
Hui Zhang   +6 more
wiley   +1 more source

Selective Effects of Acutely Administered N‐Acetyl‐Cysteine in Rodent Models of Nicotine‐Conditioned Behaviours

open access: yesAddiction Biology, Volume 30, Issue 9, September 2025.
ABSTRACT Chronic nicotine administration leads to neuroadaptations, an important process in nicotine and tobacco dependence for which treatments are limited. The cysteine pro‐drug, N‐acetyl‐cysteine (NAC), is a promising glutamatergic agent that has shown some clinical efficacy in reducing nicotine use in humans.
Kelsey Stoddart   +5 more
wiley   +1 more source

Reorganization of Mitochondrial Function and Architecture in Response to Plant‐Derived Alkaloids: Anatabine, Anabasine, and Nicotine, Investigated in SH‐SY5Y Cells and in a Cellular Model of Parkinson's Disease

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 9, September 2025.
The effects of tobacco alkaloids: anatabine, anabasine, and nicotine, were investigated in a model of mitochondrial stress, mimicking cellular pathology accompanying Parkinson's disease development. The alkaloids modulated mitochondrial function and alleviated the hallmarks of mitochondrial stress. However, they acted via slightly different mechanisms.
Dominika Malińska   +11 more
wiley   +1 more source

The Microbiota‐Gut‐Brain Connection: A New Horizon in Neurological and Neuropsychiatric Disorders

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 9, September 2025.
The microbiota‐gut‐brain axis (MGBA) is a crucial regulator of neurological and neuropsychiatric disorders, with gut microbiota dysbiosis linked to various diseases. Gut microbiota changes can lead to neurodegenerative diseases like depression, autism, schizophrenia, Parkinson's, Alzheimer's, dementia, multiple sclerosis, epilepsy, anxiety, and autism ...
Md. Faysal   +12 more
wiley   +1 more source

Involvement of Spinal Neurotrophin-3 in Electroacupuncture Analgesia and Inhibition of Spinal Glial Activation in Rat Model of Monoarthritis

open access: bronze, 2011
Wen‐Li Mi   +10 more
openalex   +1 more source

Connexin43 and Its Regulation of Astrocyte Gap Junction Function: Influencing Depression Progression by Mediating Electrical and Chemical Signals

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 9, September 2025.
A close relationship exists between Cx43‐mediated gap junction channels in astrocytes and depression. The astrocytic network formed through gap junction channels, in collaboration with neurons, participates in mediating intercellular electrochemical signaling within the nervous system.
Hongbin Wang   +11 more
wiley   +1 more source

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