Results 31 to 40 of about 58,898 (268)

Preclinical Models: Boosting Synergies for Improved Translation [PDF]

open access: yes, 2020
The field of preclinical models is a very vast arena, in which finding connections among groups acting in apparently very distant research areas can sometimes prove challenging [...
Attanasio C., Sangiovanni M.
core   +1 more source

RNA sequencing dataset describing transcriptional changes in cervical dorsal root ganglia after bilateral pyramidotomy and forelimb intramuscular gene therapy with an adeno-associated viral vector encoding human neurotrophin-3

open access: yesData in Brief, 2018
Unilateral or bilateral corticospinal tract injury in the medullary pyramids in adult rats causes anatomical and physiological changes in proprioceptive neurons projecting to the cervical spinal cord accompanied by hyperreflexia and abnormal behavioural ...
Claudia Kathe, Lawrence D.F. Moon
doaj   +1 more source

Beneficial Effects of Sulforaphane Treatment in Alzheimer's Disease May Be Mediated through Reduced HDAC1/3 and Increased P75NTR Expression

open access: yesFrontiers in Aging Neuroscience, 2017
Alzheimer's disease is an irreversible, progressive neurodegenerative disorder. The accumulation of Aβ in the brain is thought to play a causative role in the development of cognitive dysfunction in Alzheimer's disease.
Li An   +9 more
doaj   +1 more source

Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]

open access: yes, 2015
The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA   +2 more
core   +2 more sources

Training-induced gene expression plasticity in cardiac function and neural regulation for ultra-trail runners [PDF]

open access: yes, 2015
This study aims to assess the gene regulatory response from a group of 16 athletes and to observe the plasticity induced by their training regime on the gene expression response after their participation in an 82km race.
Brotons, Daniel   +4 more
core   +1 more source

Serum neurotrophin-3 and neurotrophin-4 levels are associated with asthma severity in children [PDF]

open access: yesEuropean Respiratory Journal, 2012
To the Editors: Asthma is the most common chronic disease in childhood and is characterised by chronic airway inflammation, reversible airflow obstruction and hyperresponsiveness of the airways. Among the substantial pathophysiological aspects of asthma are neuroimmune interaction mechanisms; neurotrophins are mediators of the interactions providing ...
A, Szczepankiewicz   +7 more
openaire   +2 more sources

The effect of vascular graft and human umbilical cord blood-derived CD34+ stem cell on peripheral nerve healing [PDF]

open access: yes, 2018
AIM: There are many trials concerning peripheral nerve damage causes and treatment options. Unfortunately, nerve damage is still a major problem regarding health, social and economic issues.
Abban, G.   +6 more
core   +1 more source

Crystallization and preliminary structural studies of neurotrophin‐3 [PDF]

open access: yesProtein Science, 1994
AbstractNeurotrophin‐3 (NT‐3) has been crystallized in 2 forms. Orthorhombic crystals, space group P21212, diffracted to 2.8 Å and have cell dimensions a = 39.1 Å, b = 54.0 Å, and c = 65.5 Å. The second form is space group P43212, with cell dimensions a = b = 67.1 Å, and c = 107.9 Å. The tetragonal crystals diffract to 2.8 Å at room temperature and 2.5
J A, Kelly   +3 more
openaire   +2 more sources

High abundances of neurotrophin 3 in atopic dermatitis mast cell

open access: yesJournal of Occupational Medicine and Toxicology, 2009
Background Neurotrophin 3 (NT-3) is a member of the neurotrophin family, a group of related proteins that are known to regulate neuro-immune interactions in allergic diseases.
Groneberg David A   +4 more
doaj   +1 more source

Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples [PDF]

open access: yes, 2013
Emerging evidence has shown that the tumor microenvironment plays a crucial role in prostate cancer (PCa) development and progression. However, the mechanism(s) through which stromal cells regulate epithelial cells and the differences among prostatic ...
Clemente, Luigi Di   +7 more
core   +1 more source

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