Results 61 to 70 of about 58,019 (320)
Advanced Science, EarlyView.This systematic scoping review explores conductive nanocomposite hydrogels for neural tissue engineering(NTE), focusing on composition, cellular interactions, and neural differentiation capabilities. The review synthesizes data from 125 studies, examining important features including commonly used materials, cell types, and differentiation strategies ...
Mohammad Moghaddasi +6 more
wiley +1 more source
BMC Neuroscience, 2004 Background Ischemia within the optic nerve head (ONH) may contribute to retinal ganglion cell (RGC) loss in primary open angle glaucoma (POAG). Ischemia has been reported to increase neurotrophin and high affinity Trk receptor expression by CNS neurons ...
Clark Abbot F +2 more
doaj +1 more source
Neural Regeneration Research, 2020 Neurotrophins play a major role in the regulation of neuronal growth such as neurite sprouting or regeneration in response to nerve injuries. The role of nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor in maintaining the ...
Michele Fornaro +6 more
doaj +1 more source
Neuroprotective mechanism of BNG-1 against focal cerebral ischemia: a neuroimaging and neurotrophin study. [PDF]
PLoS ONE, 2014 BNG-1 is a herb complex used in traditional Chinese medicine to treat stroke. In this study, we attempted to identify the neuroprotective mechanism of BNG-1 by using neuroimaging and neurotrophin analyses of a stroke animal model.
Nai-Fang Chi +7 more
doaj +1 more source
Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain [PDF]
, 2010 The consumption of flavonoid-rich foods and beverages has been suggested to limit the neurodegeneration associated with a variety of neurological disorders and to prevent or reverse normal or abnormal deteriorations in cognitive performance.
Spencer, Jeremy Paul
core +1 more source
The Role of Differentially Expressed miRNAs and Potential miRNA-mRNA Regulatory Network in Prostate Cancer Progression and Metastasis [PDF]
, 2020 Purpose: Aberrant expression of microRNAs (miRNAs) has been discovered in prostate cancer progression however their function is not well understood, thereby further investigation is required to understand the importance of underlying mechanisms and their
Arisan, E.D. +9 more
core +1 more source
A New Role for Neurotrophin-3 [PDF]
The American Journal of Pathology, 1998 Nervous system and hair follicle epithelium share a common ectodermal origin, and some neurotrophins (NTs) can modulate keratinocyte proliferation and apoptosis. Therefore, it is reasonable to ask whether NTs are also involved in hair growth control.
Botchkarev, V A +9 more
openaire +4 more sources
Advanced Science, EarlyView.We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich +8 more
wiley +1 more source
The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain [PDF]
, 2016 The neurotrophin family of growth factors, comprised of nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin 3 (NT3), and neurotrophin 4 (NT4), is implicated in the physiology of chronic pain.
Angus Nedderman +17 more
core +3 more sources
Advanced Science, EarlyView.pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou +7 more
wiley +1 more source