Results 201 to 210 of about 26,439 (246)
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Neurotrophin receptors

Progress in Neurobiology, 1994
The neurotrophins are members of a family of four related proteins that allow the survival and differentiation of specific sub-sets of embryonic vertebrate neurons. On neurons, two types of neurotrophin receptors can be distinguished on the basis of their dissociation constants: low affinity receptors (Kd 10(-9) M) and high affinity receptors (Kd 10 ...
G, Dechant   +2 more
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Endocytic trafficking of neurotrophins in neural development

open access: yesTrends in Cell Biology, 2012
Item does not contain fulltextDuring the formation of neuronal circuits, neurons respond to diffusible cues secreted by target tissues. Often, target-derived signals act on nerve terminals to influence local growth events; in other cases, they are ...
Rejji Kuruvilla, Daniel Bodmer
exaly   +2 more sources

Neurotrophins and Neurotrophin Receptors in Human Lung Cancer

American Journal of Respiratory Cell and Molecular Biology, 2001
Abstract The expression of neurotrophins (NTs) and related high- and low-affinity receptors was studied in surgical samples of histologically diagnosed human tumors of the lower respiratory tract. The experiment was conducted with 30 non–small cell lung cancer specimens and in eight small cell lung cancer specimens by Western blot ...
RICCI, Alberto   +9 more
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Neurotrophins and acupuncture

Autonomic Neuroscience, 2010
The aim of this review is to report recent findings and ongoing studies on the effects of acupuncture on endogenous biological mediators, in particular on neurotrophins such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). Acupuncture is a therapeutic technique and is a part of Traditional Chinese Medicine (TCM).
Luigi Manni   +4 more
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Functional Interactions of Neurotrophins and Neurotrophin Receptors

Annual Review of Neuroscience, 1995
Hypothesis Programmed neuronal cell death is a prominent feature of vertebrate embryonic development. Timing and extent of cell death are dependent on the influence of the targets those neurons innervate, The number of neurons in the adult nervous system and the density of innervation of their targets are determined by a competitive process in which ...
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Neurotrophin and Neurotrophin Receptors in Islet Cells

Hormone and Metabolic Research, 1997
A large number of proteins are found specifically in insulin-producing cells and in neuronal cells. The function of neurotrophins in beta cells and the molecular mechanism leading to their expression include the expression of functional receptors for different neurotrophins.
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Neurotrophins in odontogenesis

The International Journal of Developmental Biology, 1995
Neurotrophins (NTFs) are a family of structurally related proteins with specific effects on the developing nervous system and a wide range of non-neuronal differentiating cells. To date, four NTFs have been characterized: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4).
T A, Mitsiadis, K, Luukko
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Neurotrophins and Migraine

2017
Neurotrophins (NTs) have been implicated in generation and modulation of nociceptive pathways. Change in NTs levels is associated with painful conditions and neurological diseases such as migraine. Currently, it is generally recognized that migraine headaches result from the activation and sensitization of trigeminal sensory afferent fibers leading to ...
L B, Martins   +2 more
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Neurotrophin signaling through the p75 neurotrophin receptor

Progress in Neurobiology, 2002
The neurotrophins are growth factors that play critical roles in the development, maintenance, survival, and death of the nervous system. The signal transducing systems that mediate the diverse biological functions of the neurotrophins are initiated by their interactions with two categories of cell surface receptors, the Trk family of tyrosine kinases ...
Philippe P, Roux, Philip A, Barker
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Neurotrophins and depression

Trends in Pharmacological Sciences, 1999
Exogenous delivery of the neurotrophic factors, brain-derived neurotrophic factor (BDNF) or neurotrophin-3 (NT-3), promotes the function, sprouting and regrowth of 5-HT-containing neurones in the brains of adult rats. Similar infusions of BDNF into the dorsal raphe nucleus produce an antidepressant effect, as evaluated by several 'learned helplessness'
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