Results 111 to 120 of about 1,027,075 (269)

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

open access: yesAdvanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang   +12 more
wiley   +1 more source

Optic nerve and chiasma compression by a dolichoectatic internal carotid artery - An unusual type of neurovascular conflict. Value of MR and MRA - Case report

open access: yes, 1998
We describe an unusual type of neurovascular conflict between an elongated internal carotid artery and the optic nerve-chiasma complex. The fundamental role of conventional MR and MR angiography in the demonstration of the neurovascular conflict is ...
ALAFACI, Concetta   +6 more
core  

Vascular Compression of Medulla Oblongata by Non-Dolichoectatic Vertebral Artery

open access: yesIndian Journal of Neurosurgery
Neurovascular conflicts are common in the posterior fossa and basal cisterns due to coexistence of important neural and vascular structures. Neurovascular conflict arising from compression of the cranial nerves by pulsatile flow in the adjacent ...
V. Nitheesha Reddy   +3 more
doaj   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

open access: yesAdvanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong   +5 more
wiley   +1 more source

Navigating the neurovascular maze of trigeminal neuralgia

open access: yesRadiology Case Reports
Tic douloureux, also known as trigeminal neuralgia, is distinguished by recurrent episodes of severe, lancinating pain that affects one or more branches of the trigeminal nerve, representing a prevalent pain syndrome.
Devyansh Nimodia, MBBS   +5 more
doaj   +1 more source

Artificial Intelligence‐Driven Network Pharmacology: A Methodological Paradigm Shift Bridging Traditional Wisdom and Modern Science

open access: yesAdvanced Intelligent Discovery, EarlyView.
Artificial intelligence is redefining network pharmacology (NP). By integrating knowledge graph engineering, geometric deep learning, multiomics anchoring, and generative reasoning, AI‐driven NP (AI‐NP) transforms static target mapping into dynamic, predictive modeling.
Cong Wang   +9 more
wiley   +1 more source

Trigeminal neuralgia at the present stage: Pathophysiology, classification, diagnosis and treatment (literature review)

open access: yesActa Biomedica Scientifica
The incidence of trigeminal neuralgia (TN) is 4–5 cases per 100,000 population per year, and the prevalence is about 20–50 cases per 100,000 population.
A. N. Zhurkin   +5 more
doaj   +1 more source

Magnetic Field Control Using an Electromagnetic Actuation System with Combined Air‐Core and Metal‐Core Coils

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
An electromagnetic manipulation system enhances magnetic field strength in the Z‐direction for 3D control of microrobots and nanoparticles. Featuring eight metal‐core coils and two air‐core coils arranged hemispherically, it ensures unimpeded workspace access and integrates imaging tools.
Nader Latifi Gharamaleki   +4 more
wiley   +1 more source

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