Results 81 to 90 of about 1,167,955 (270)

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

MINIMALLY INVASIVE ENDOSCOPIC TREATMENT OF GLOSSOPHARYNGEAL NEURALGIA USING A BURR-HOLE TECHNIQUE: CASE SERIES

Паёми Сино
Glossopharyngeal neuralgia (also known as Sicard syndrome) is a rare cranial nerve compression syndrome that significantly impacts a patient's quality of life.
Chobulov Sunatullo Aladostovich, Ashurov Rakhmonkul Gurezovich, Shoev Sadullo Nazrulloevich, Kholmurodov Mekhrob Makhmadaminovich   +3 more
doaj   +1 more source

Optic nerve and chiasma compression by a dolichoectatic internal carotid artery - An unusual type of neurovascular conflict. Value of MR and MRA - Case report

, 1998
We describe an unusual type of neurovascular conflict between an elongated internal carotid artery and the optic nerve-chiasma complex. The fundamental role of conventional MR and MR angiography in the demonstration of the neurovascular conflict is ...
ALAFACI, Concetta, BLANDINO, Alfredo, SALPIETRO, Francesco, BRAMANTI, Placido, NARBONE, Maria Carola, PANDOLFO, Ignazio, LONGO, Marcello   +6 more
core  

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Advanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang, Yike Wang, Matthew R. Lowerison, Yue Xu, Murong Yi, Bing‐Ze Lin, YiRang Shin, Nathiya Vaithiyalingam Chandra Sekaran, Daniel A. Llano, Pengfei Song   +9 more
wiley   +1 more source

Radiation Protection of Staff and Patients in Cardiovascular and Neurovascular Imaging

, 2015
DOSIMETRY AND RADIATION PROTECTION - Radiation Protection of Staff and Patients in Cardiovascular and Neurovascular ...
Padovani, Renato, Rehani, Madan, Vano, Eliseo, CAVEDON, CARLO   +3 more
core   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

Advanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu, Zichao Huang, Xi Rong, Xingwei Lei, Fuming Liang, Xiaoguo Li, Jiru Zhou, Yu Wang, Yifan Huang, Shuang Tang, Jianjun Zhong, Jin Yan, Hongji Deng, Chun Zeng, Zongduo Guo   +14 more
wiley   +1 more source

Cranial nerve rhizopathies caused by cerebellopontine angle mass lesions and coexisting neurovascular conflict: systematic review and case illustration

Interdisciplinary Neurosurgery
Introduction: Cranial nerve rhizopathies caused by CPA pathology are challenging to manage due to the region’s complex anatomy, which contains multiple cranial nerves and vascular structures.
George Rudd, Eric Suero Molina, Kevin Agyemang, Angelo Jayamanne, Antonio Di Ieva   +4 more
doaj   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Microvascular decompression in classical trigeminal neuralgia: analysis of long-term outcome, complications, and risk factors for treatment failure

Interdisciplinary Neurosurgery
Objective: Trigeminal neuralgia (TN) is one of the most severe pain sensations and is often not sufficiently manageable with pharmacotherapy. Microvascular decompression (MVD) is considered the most effective long-term treatment for classical TN.
Majd A. Alkhatib, MD, Johann Klein, MD, Amer Alkhodary, MD, Thomas Pinzer, MD, Gabrielle Schackert, MD, Ilker Y. Eyüpoglu, MD, Tareq A. Juratli, MD   +6 more
doaj   +1 more source