Results 191 to 200 of about 14,410 (259)

Defying gravity: Breath, beat and brain

Experimental Physiology, EarlyView.
Shigehiko Ogoh, Damian Miles Bailey
wiley   +1 more source

Amyloid β alters vascular CaV1.2 channel spatiotemporal properties

The Journal of Physiology, EarlyView.
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor, Miguel Martin‐Aragon Baudel, Eric Pereira da Silva, Johannes W. Hell, Madeline Nieves‐Cintron, Manuel F. Navedo   +5 more
wiley   +1 more source

Psychedelic 5-HT_2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function. [PDF]

Nat Neurosci
Padawer-Curry JA, Krentzman OJ, Kuo CC, Wang X, Bice AR, Nicol GE, Snyder AZ, Siegel JS, McCall JG, Bauer AQ.   +9 more
europepmc   +1 more source

Cerebral blood flow response to dynamic resistance exercise

Experimental Physiology, EarlyView.
Stephanie Korad, Toby Mündel, Blake G. Perry   +2 more
wiley   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Neurovascular coupling assessment by transcranial doppler in acute stroke could be informative of long-term cognitive status. [PDF]

J Cereb Blood Flow Metab
Ferreira J, Alves F, Pedro T, Fonseca L, Gama G, Moreira G, Azevedo E, Castro P.   +7 more
europepmc   +1 more source

A computational model for retinal haemodynamics under gravitational and postural variations

The Journal of Physiology, EarlyView.
Abstract figure legend The haemodynamic impact of gravitational and postural changes on the retina, and its relevance to spaceflight associated neuro‐ocular syndrome (SANS), remains incompletely characterized. This study assesses retinal haemodynamics from upright to head‐down tilt using a lumped‐parameter model that dynamically couples intraocular ...
Michele Nigro, Andrea Montanino, Eduardo Soudah   +2 more
wiley   +1 more source

<i>In vivo</i> two-photon microscopy for studies of neurovascular coupling in rodents: a beginner's guide. [PDF]

Neurophotonics
Lind BL, Kucharz K, Cai C.
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Chronic impairment of neurovascular coupling and cognitive decline in young survivors of severe traumatic brain injury. [PDF]

Geroscience
Magyar-Sumegi ZD, Csendes M, Lendvai-Emmert D, Sebestyen G, Tamas V, Bandi S, Czigler A, Yabluchanskiy A, Tarantini S, Ungvari Z, Czeiter E, Amrein K, Orsi G, Perlaki G, Buki A, Toth P.   +15 more
europepmc   +1 more source