Results 171 to 180 of about 15,500 (253)

The High‐Intensity Zone: A Dynamic Inflammatory Hub in Lumbar Disc Degeneration

Orthopaedic Surgery, EarlyView.
The HIZ, a dynamic inflammatory hub in lumbar disc degeneration, links inflammation‐degeneration‐pain; integrating advanced diagnostics and targeted therapies offers precise management for discogenic low back pain. ABSTRACT The lumbar intervertebral disc high‐intensity zone (HIZ), a focal hyperintensity within the annulus fibrosus on T2‐weighted ...
Qi Zhou, Jingyi Cai, Weijian Zhu, Sirui Zhou, Liling Zhou, Yiyao Pei, Gang Wu   +6 more
wiley   +1 more source

A deep learning pipeline for mapping in situ network-level neurovascular coupling in multi-photon fluorescence microscopy. [PDF]

Elife
Rozak MW, Mester JR, Attarpour A, Dorr A, Patel S, Koletar M, Hill ME, McLaurin J, Goubran M, Stefanovic B.   +9 more
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Surgical considerations based on oral and periodontal vascularization

Periodontology 2000, EarlyView.
Abstract Objectives To synthesize current evidence on vascular and anastomotic patterns, emphasizing their operative implications for optimizing flap perfusion, neovascularization, and wound healing in periodontal and implant surgery, while accounting for anatomical variability and collateral circulation. Materials and Methods A comprehensive review of
Arvin Shahbazi, Edward P. Allen, Sebastian Gschwindt, Kevin G. Murphy, Gábor Baksa, Anton Sculean   +5 more
wiley   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

High-caloric intake rescues early symptomatic AD-induced hippocampal neurovascular coupling deficits. [PDF]

Alzheimers Dement
Almanza DLV, Trevisiol A, Koletar MM, Lai AY, Ribeiro JA, Hill ME, Stanisz GJ, McLaurin J, Stefanovic B.   +8 more
europepmc   +1 more source

Finding the Words: How Does the Aging Brain Process Language? A Focused Review of Brain Connectivity and Compensatory Pathways

Topics in Cognitive Science, EarlyView.
Abstract As people age, there is a natural decline in cognitive functioning and brain structure. However, the relationship between brain function and cognition in older adults is neither straightforward nor uniform. Instead, it is complex, influenced by multiple factors, and can vary considerably from one person to another.
Monica Baciu, Elise Roger
wiley   +1 more source

Direct Evidence for the Feedforward Neurovascular Coupling Mechanism in Humans During Task Onset: An EEG-fNIRS-TCD Multimodal Imaging Study. [PDF]

Sensors (Basel)
Burma JS, Neill MG, Fletcher EKS, Seok J, Johnson NE, Schneider KJ, Debert CT, Dunn JF, Smirl JD.   +8 more
europepmc   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

Experimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr, Philip N. Ainslie, Trevor Day   +2 more
wiley   +1 more source

Altered neurovascular coupling in patients with human immunodeficiency virus-associated asymptomatic neurocognitive impairment: a multimodal magnetic resonance imaging study. [PDF]

Quant Imaging Med Surg
Chen J, Xu F, Li A, Wang X, Wang W, Li H.   +5 more
europepmc   +1 more source