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The contribution of astrocyte signalling to neurovascular coupling
Brain Research Reviews, 2010The tight spatial and temporal coupling between neuronal activity and blood flow ensures that active brain regions receive an adequate supply of oxygen and energetic metabolites. There clearly is still an enormous amount of experimental and theoretical work to be done to unravel the precise mechanism of neurovascular coupling, but over the last decade ...
Carmignoto, Giorgio, GomezGonzalo, Marta
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Fractional dynamical model for neurovascular coupling
2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2014The neurovascular coupling is a key mechanism linking the neural activity to the hemodynamic behavior. Modeling of this coupling is very important to understand the brain function but it is at the same time very complex due to the complexity of the involved phenomena.
Zehor Belkhatir +1 more
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Metabolic Aspects of Neurovascular Coupling
1997In the previous chapter it was demonstrated that functional neuroimaging relies on the coupling of neuronal activity and cerebral blood flow. What is the function of neurovascular coupling? Does it serve to provide a constant glucose or oxygen delivery to brain cells? Does it mainly regulate removal of tissue metabolites such as lactate?
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Neurovascular Coupling During Spreading Depolarizations
2012Injury depolarizations akin to spreading depression of Leão are important in the progression of tissue damage in ischemic stroke, intracranial hemorrhage, and trauma. Much of the research on injury depolarizations has been focused on their origins, electrophysiological mechanisms, and metabolic impact.
Ulrike, Hoffmann, Cenk, Ayata
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Angiotensin and Neurovascular Coupling: Beyond Hypertension
Microcirculation, 2015AbstractBrain homeostasis is dependent upon the constant perfusion of oxygen and nutrients through CBF. The mechanism responsible to couple CBF to neuronal activity is termed NVC. Ang II, a key player in hypertension, impairs NVC and has been found to be of significant importance in neurodegenerative diseases, such as AD. The presence of Ang II and its
Sherri, Bloch +2 more
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Nitric oxide is fundamental to neurovascular coupling in humans.
Journal of Physiology, 2020Hannah G Caldwell +2 more
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What is the key mediator of the neurovascular coupling response?
Neuroscience and Biobehavioral Reviews, 2019Patrick S Hosford, Alexander V Gourine
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