Results 151 to 160 of about 972,165 (184)

Neurovascular coupling mechanisms in health and neurovascular uncoupling in Alzheimer's disease. [PDF]

Brain, 2022
To match the metabolic demands of the brain, mechanisms have evolved to couple neuronal activity to vasodilation, thus increasing local cerebral blood flow and delivery of oxygen and glucose to active neurons.
Brad A. Sutherland, Daniel J Beard, Gabriele C Deluca   +2 more
exaly   +5 more sources

Neurovascular coupling and distribution of cerebral blood flow during exercise

Journal of Neuroscience Methods, 2011
We examined how cerebral blood flow velocity (CBV) and neurovascular coupling is influenced by exercise. Blood velocities in the posterior and middle cerebral arteries (PCAv and MCAv) during rest and cycling exercise at 60% estimated maximal oxygen ...
Philip N Ainslie, Shieak Tzeng, Kurt J Smith   +2 more
exaly   +2 more sources

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Heritability of brain neurovascular coupling

Journal of Neurophysiology, 2022
Here we show that the sample-to-sample turnover of the resting state fMRI blood-oxygen-level-dependent turnover (TBOLD) is heritable, the left and right hemisphere TBOLD heritabilities are highly correlated, and TBOLD heritability varies among cortical areas.
Peka Christova, Kâmil Uğurbil, Apostolos P. Georgopoulos   +2 more
openaire   +2 more sources

Spreading Depression and Neurovascular Coupling [PDF]

Stroke, 2013
Spreading depression, discovered by Leao in 1944,1 is an intense depolarization wave that slowly propagates (≈3 mm/min) in gray matter by way of contiguity, regardless of functional divisions or arterial territories. The depolarization is associated with massive transmembrane ionic and water shifts coupled to a surge in extracellular K+ and ...
Cenk Ayata
exaly   +3 more sources

Neurovascular coupling: motive unknown

Trends in Neurosciences, 2022
In the brain, increases in neural activity drive changes in local blood flow via neurovascular coupling. The common explanation for increased blood flow (known as functional hyperemia) is that it supplies the metabolic needs of active neurons. However, there is a large body of evidence that is inconsistent with this idea.
openaire   +2 more sources

Is Neurovascular Coupling of Relevance in Glaucoma?

Survey of Ophthalmology, 2007
Rapid development of functional neuroimaging techniques have brought about a growing interest for neurovascular coupling in neuroresearch, which, in turn, has prompted similar research in ophthalmology. There are now hints that neurovascular coupling is disturbed in glaucoma.
Konstantin, Gugleta, Gabriele, Fuchsjäger-Mayrl, Selim, Orgül   +2 more
openaire   +2 more sources

Ethanol modulates the neurovascular coupling

NeuroToxicology, 2013
Despite some evidence of the underlying molecular mechanisms the neuronal basis of ethanol-induced effects on the neurovascular coupling that forms the BOLD (blood oxygenation level dependent) signal is poorly understood. In a recent fMRI (functional magnetic resonance imaging) study monitoring ethanol-induced changes of the BOLD signal a reduction of ...
Michael, Luchtmann, Katja, Jachau, Daniela, Adolf, Friedrich-Wilhelm, Röhl, Sebastian, Baecke, Ralf, Lützkendorf, Charles, Müller, Johannes, Bernarding   +7 more
openaire   +2 more sources

Modeling of the Neurovascular Coupling in Epileptic Discharges

Brain Topography, 2011
Despite the interest in simultaneous EEG-fMRI studies of epileptic spikes, the link between epileptic discharges and their corresponding hemodynamic responses is poorly understood. In this context, biophysical models are promising tools for investigating the mechanisms underlying observed signals.
Voges, Nicole, Blanchard, Solenna, Wendling, Fabrice, David, Olivier, Benali, Habib, Papadopoulo, Théodore, Clerc, Maureen, Bénar, Christian   +7 more
openaire   +4 more sources

The role of nitric oxide in neurovascular coupling

Journal of Theoretical Biology, 2016
Nitric oxide (NO) is a neurotransmitter known to act as a potent cerebral vasodilator. Its role in neurovascular coupling (NVC) is discussed controversially and one of the main unanswered questions is which cell type provides the governing source of NO for the regulation of vasodynamics.
Dormanns, K., Brown, R. G., David, T.
openaire   +2 more sources

Investigating static nonlinearities in neurovascular coupling

Magnetic Resonance Imaging, 2011
Many statistical models of coupling between time changes of the band-limited power of neural signals and functional magnetic resonance imaging Blood Oxygenation Level Dependent (BOLD) signal time changes rely on linear convolution. The effect of nonlinear behaviors in single-trial relationships between neural signals and BOLD responses is rarely tested
Logothetis, Nikos, Magri, Cesare, Logothetis, Nikos K., Panzeri, Stefano   +3 more
openaire   +3 more sources