Results 1 to 10 of about 32,368 (114)
Toward three-dimensional in vitro models to study neurovascular unit functions in health and disease
Neural Regeneration Research, 2021 The high metabolic demands of the brain require an efficient vascular system to be coupled with neural activity to supply adequate nutrients and oxygen. This supply is coordinated by the action of neurons, glial and vascular cells, known collectively as ...
Tara M Caffrey +2 more
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Structure and function of neurovascular unit in arterial hypertension [PDF]
Frontiers in Molecular NeuroscienceArterial hypertension is considered a main risk factor for cognitive impairment and stroke. Although chronic hypertension leads to adaptive changes in the lager cerebral blood vessels which should protect the downstream microvessels, profound changes in ...
Ewa Kozniewska, Marta Aleksandrowicz
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Oxidative Stress and the Neurovascular Unit
Life, 2021 The neurovascular unit (NVU) is a relatively recent concept that clearly describes the relationship between brain cells and their blood vessels. The components of the NVU, comprising different types of cells, are so interrelated and associated with each ...
Carmela Rinaldi +5 more
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Neurobiology of DiseaseVascular cognitive impairment (VCI) is a progressive cognitive impairment caused by cerebrovascular disease or vascular risk factors. It is the second most common type of cognitive impairment after Alzheimer's disease. The pathogenesis of VCI is complex,
Zhidong He, Jing Sun
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Characterization of the biochemical and behavioral effects of cannabidiol: implications for migraine
The Journal of Headache and Pain, 2023 Cannabidiol (CBD) is the main pharmacologically active phytocannabinoid. CBD exerts an analgesic effect in several pain models, does not have side effects and has low toxicity. The data about CBD mechanisms of action in pain and its therapeutic potential
Rosaria Greco +9 more
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Cells, 2022 Calcitonin-gene-related peptide (CGRP) plays a key role in migraine pathophysiology and more specifically in the mechanisms underlying peripheral and central sensitization.
Rosaria Greco +4 more
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Scientific Reports, 2023 Misfolding of α-synuclein (α-Syn) in the brain causes cellular dysfunction, leading to cell death in a group of neurons, and consequently causes the progression of Parkinson’s disease (PD).
Jin-Young Jeong +5 more
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Medicina, 2021 Background and Objectives: A hospital-based stroke registry is a useful tool for systematic analyses of the epidemiology, clinical characteristics, and natural course of stroke. Analyses of stroke registry data can provide information that can be used by
Guntis Karelis +6 more
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Functional Brain Imaging Based on the Neurovascular Unit for Evaluating Neural Networks after Strok [PDF]
Advanced Ultrasound in Diagnosis and Therapy, 2022 The exploration of human brain function has always been a research hotspot in the field of neuroscience. The concept of a neurovascular unit suggests that cerebral microcirculation can be used as a reliable signal to reflect neural function. Accordingly,
Yongyue Zhang, MM, Yang Sun, MM, Li Zhang, MM, Rongjin Zhang, MM, Shumin Wang, PhD
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Cells, 2021 The endocannabinoid system exerts an important role in pain processing and modulation. Modulation of the system with hydrolase inhibitors of anandamide (AEA) or 2-arachidonyl glycerol (2-AG) has proved effective in reducing migraine-like features in ...
Rosaria Greco +4 more
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