Results 31 to 40 of about 2,153,529 (297)

The Translational Significance of the Neurovascular Unit [PDF]

open access: yesJournal of Biological Chemistry, 2017
The mammalian brain is supplied with blood by specialized vasculature that is structurally and functionally distinct from that of the periphery. A defining feature of this vasculature is a physical blood-brain barrier (BBB). The BBB separates blood components from the brain microenvironment, regulating the entry and exit of ions, nutrients ...
Heather L, McConnell   +3 more
openaire   +2 more sources

Vasculo-Neuronal Coupling and Neurovascular Coupling at the Neurovascular Unit: Impact of Hypertension [PDF]

open access: yesFrontiers in Physiology, 2020
Components of the neurovascular unit (NVU) establish dynamic crosstalk that regulates cerebral blood flow and maintain brain homeostasis. Here, we describe evidence for cells of the NVU contributing to critical physiological processes such as cerebral autoregulation, neurovascular coupling, and vasculo-neuronal coupling.
Jessica L. Presa   +4 more
openaire   +4 more sources

tPA and Proteolysis in the Neurovascular Unit [PDF]

open access: yesStroke, 2004
One of the major recommendations emerging from the NINDS Stroke Progress Review Group was to shift the emphasis from a purely neurocentric view of cell death toward a more integrative approach whereby responses in all brain cells and matrix are considered during cerebral ischemia (see Figure).
Eng H, Lo   +2 more
openaire   +2 more sources

Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model

open access: yesNature Communications, 2023
The anion channel SLAC1 functions as a crucial effector in the ABA signaling, leading to stomata closure. SLAC1 is activated by phosphorylation in its intracellular domains.
Yeongmok Lee   +10 more
doaj   +1 more source

In vivo imaging of the neurovascular unit in CNS disease. [PDF]

open access: yes, 2012
The neurovascular unit-comprised of glia, pericytes, neurons and cerebrovasculature-is a dynamic interface that ensures physiological central nervous system (CNS) functioning.
Merlini, Mario   +2 more
core   +1 more source

Neurovascular complications in displaced extension-type supracondylar fractures in children : outcome of conservative management [PDF]

open access: yes, 2010
Includes bibliographical referencesThe aim of our study was to review our conservative management of neurovascular complications in displaced extension-type supracond ylar fractures of the humerus in children. We critically analysed the outcomes.
Louw, Frederik Marthinus
core   +1 more source

Pericyte Signaling in the Neurovascular Unit [PDF]

open access: yesStroke, 2009
Brain pericytes are intimately associated with capillary endothelial cells, separated only by basement membrane. Pericyte research has been hampered by absence of pericyte-specific immunochemical markers. The vast array of pericyte functions include contractility, immunologic, migratory, and angiogenic. Pericytes have stem cell potential, contribute to
openaire   +2 more sources

Innate Immunity Cells and the Neurovascular Unit [PDF]

open access: yesInternational Journal of Molecular Sciences, 2018
Recent studies have clarified many still unknown aspects related to innate immunity and the blood-brain barrier relationship. They have also confirmed the close links between effector immune system cells, such as granulocytes, macrophages, microglia, natural killer cells and mast cells, and barrier functionality.
Ivan Presta   +9 more
openaire   +4 more sources

Chronic stress induced disruption of the peri-infarct neurovascular unit following experimentally induced photothrombotic stroke

open access: yes, 2017
How stress influences brain repair is an issue of considerable importance, as patients recovering from stroke are known to experience high and often unremitting levels of stress post-event.
Lin Kooi Ong   +9 more
core   +1 more source

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