Results 21 to 30 of about 2,153,529 (297)

The Neurovascular Unit Dysfunction in Alzheimer’s Disease [PDF]

International Journal of Molecular Sciences, 2021
Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide. Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and aggregates of amyloid β peptide (Aβ) both in the brain parenchyma as neuritic plaques, and around blood vessels as cerebral amyloid angiopathy (CAA).
Luis O. Soto-Rojas, Mar Pacheco-Herrero, Paola A. Martínez-Gómez, B. Berenice Campa-Córdoba, Ricardo Apátiga-Pérez, Marcos M. Villegas-Rojas, Charles R. Harrington, Fidel de la Cruz, Linda Garcés-Ramírez, José Luna-Muñoz   +9 more
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The Neurovascular Unit in Fetal Growth Restriction

, 2023
This thesis examines the development of the neurovascular unit, a collection of cells and surrounding structures controlling blood flow within the brain.
ALEXANDER HENRY BELL (15216007)
core   +1 more source

Aging and the neurovascular unit [PDF]

Annals of the New York Academy of Sciences, 2012
With the demonstration that acute recanalization of obstructed symptomatic cerebral arteries during ischemic stroke can result in substantial improvement in clinical outcome, the variability in clinical responses, and in hemorrhagic transformation, requires attention.
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Injury and repair in the neurovascular unit [PDF]

Neurological Research, 2012
The neurovascular unit provides a conceptual framework for investigating the pathophysiology of how brain cells die after stroke, brain injury, and neurodegeneration. Emerging data now suggest that this concept can be further extended. Cell-cell signaling between neuronal, glial, and vascular elements in the brain not only mediates the mechanisms of ...
Changhong, Xing, Kazuhide, Hayakawa, Josephine, Lok, Ken, Arai, Eng H, Lo   +4 more
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Validation of Repeated Endothelial Function Measurements Using EndoPAT in Stroke

Frontiers in Neurology, 2017
BackgroundDecreased endothelial function (EF) may be a prognostic marker for stroke. Measuring pharmacological effects on EF may be of interest in the development of personalized medicine for stroke prevention.
Aina S. Hansen, Jawad H. Butt, Sonja Holm-Yildiz, William Karlsson, Christina Kruuse   +4 more
doaj   +1 more source

TWEAK and Fn14 in the Neurovascular Unit [PDF]

Frontiers in Immunology, 2013
The neurovascular unit (NVU) is a dynamic structure assembled by endothelial cells (EC), a basement membrane (BM), perivascular astrocytes (PA), pericytes, and surrounding neurons. The NVU regulates the passage of substances and cellular elements from the intravascular space into the brain parenchyma.
openaire   +3 more sources

Factors associated with abnormal cerebral blood flow in Egyptian children with sickle cell disease

Clinical and Translational Neuroscience, 2020
Background: Transcranial Doppler (TCD) is a well-established tool for cerebrovascular assessment. Estimating the flow velocity across the intracranial arteries helps to identify children with sickle cell anaemia who are at risk for stroke. Objective: Our
Foad Abd-Allah, Mona Eltagui, Alshaimaa Mahmoud Aboulfotooh, Nirmeen Adel Kishk, Mohammad Ahmed Farrag, Sandra Ahmed Mohammed, Reham Mohammed Shamloul, Shaimaa El-Jaafary, Fadwa Said, Ahmed Ibrahim, Mona Elghamrawy   +10 more
doaj   +1 more source

Potentiation of endocannabinoids and other lipid amides prevents hyperalgesia and inflammation in a pre-clinical model of migraine

The Journal of Headache and Pain, 2022
Targeting fatty acid amide hydrolase (FAAH) is a promising therapeutic strategy to combat certain forms of pain, including migraine headache. FAAH inhibitors, such as the O-biphenyl-3-yl carbamate URB597, have been shown to produce anti-hyperalgesic ...
Rosaria Greco, Chiara Demartini, Anna Maria Zanaboni, Miriam Francavilla, Angelo Reggiani, Natalia Realini, Rita Scarpelli, Daniele Piomelli, Cristina Tassorelli   +8 more
doaj   +1 more source

Cortical organotypic slice cultures as a tool to analyze the neurovascular unit in hypoxia/ischemia and hypothermia-induced neuroprotection [PDF]

, 2013
Neurons and glial cells of the central nervous system (CNS) communicate and work together to function and execute an array of complex tasks. In addition to them a third cell type which also works to keep the brain alive are the cerebral endothelial cells
Chip, Sophorn
core   +1 more source

The Role of the Microbiome and the Neurovascular Unit. [PDF]

Surg Clin North Am
The gut-brain axis plays a crucial role in neurovascular diseases, linking gut microbiota to blood-brain barrier integrity, neuroinflammation, and disease progression. Conditions such as cerebral cavernous malformations, traumatic brain injury, radiation-induced damage, and stroke exhibit microbiome-driven modulation that may be relevant to explain ...
Polster SP.
europepmc   +3 more sources