Results 11 to 20 of about 34,675 (249)

Pathology of the neurovascular unit in leukodystrophies

open access: yesActa Neuropathologica Communications, 2021
The blood–brain barrier is a dynamic endothelial cell barrier in the brain microvasculature that separates the blood from the brain parenchyma. Specialized brain endothelial cells, astrocytes, neurons, microglia and pericytes together compose the ...
Parand Zarekiani   +5 more
doaj   +2 more sources

How does neurovascular unit dysfunction contribute to multiple sclerosis?

open access: yesNeurobiology of Disease, 2023
Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system (CNS) and the most common non-traumatic cause of neurological disability in young adults.
Jake M. Cashion   +2 more
doaj   +2 more sources

Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression

open access: yesNeural Regeneration Research, 2019
Previous studies have shown that models of depression exhibit structural and functional changes to the neurovascular unit. Thus, we hypothesized that diabetes-related depression might be associated with damage to the hippocampal neurovascular unit.
Jian Liu   +6 more
doaj   +2 more sources

The phase coherence of the neurovascular unit is reduced in Huntington’s disease [PDF]

open access: yesBrain Communications
Huntington’s disease is a neurodegenerative disorder in which neuronal death leads to chorea and cognitive decline. Individuals with ≥40 cytosine–adenine–guanine repeats on the interesting transcript 15 gene develop Huntington’s disease due to a mutated ...
Gemma Lancaster   +2 more
exaly   +7 more sources

The neurovascular unit in leukodystrophies: towards solving the puzzle [PDF]

open access: yes, 2022
The neurovascular unit (NVU) is a highly organized multicellular system localized in the brain, formed by neuronal, glial (astrocytes, oligodendrocytes, and microglia) and vascular (endothelial cells and pericytes) cells.
Nogueira Pinto, Henrique   +4 more
core   +2 more sources

Fibrinogen and Neuroinflammation in the Neurovascular Unit in Stroke. [PDF]

open access: yesJ Inflamm Res
Yi Chen,1 Lu Han,1 De-Sheng Zhu,1,2 Yang-Tai Guan1,3 1Department of Neurology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, People’s Republic of China; 2Department of Neurology, Baoshan Branch, Renji Hospital ...
Chen Y, Han L, Zhu DS, Guan YT.
europepmc   +2 more sources

Translational challenges of remote ischemic conditioning in ischemic stroke – a systematic review

open access: yesAnnals of Clinical and Translational Neurology, 2021
Remote ischemic conditioning (RIC) has well‐established cardioprotective effects in preclinical studies and promising results in preclinical stroke research.
Line Fuglsang Hansen   +3 more
doaj   +1 more source

Investigation of Phosphatidylserine-Transporting Activity of Human TMEM16C Isoforms

open access: yesMembranes, 2022
Lipid scrambling is a rapid process that dissipates the asymmetrical distribution of phospholipids in the plasma membrane. It is involved in various physiological functions such as blood coagulation and apoptosis.
Hanggu Kim   +2 more
doaj   +1 more source

Estrogen modulation of cortical spreading depression

open access: yesThe Journal of Headache and Pain, 2023
Background and aims Cortical spreading depression (CSD), a transient neuronal and glial depolarization that propagates slowly across the cerebral cortex, is the putative electrophysiological event underlying migraine aura and a headache trigger. Migraine
Chiho Kudo   +4 more
doaj   +1 more source

Construction and imaging of a neurovascular unit model

open access: yesNeural Regeneration Research, 2022
In 2001, the concept of the neurovascular unit was introduced at the Stroke Progress Review Group meeting. The neurovascular unit is an important element of the health and disease status of blood vessels and nerves in the central nervous system.
Taiwei Dong   +4 more
doaj   +1 more source

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