Results 11 to 20 of about 2,245,425 (289)
Pathology of the neurovascular unit in leukodystrophies [PDF]
Acta Neuropathologica Communications, 2021 The blood–brain barrier is a dynamic endothelial cell barrier in the brain microvasculature that separates the blood from the brain parenchyma. Specialized brain endothelial cells, astrocytes, neurons, microglia and pericytes together compose the ...
Wolf, Nicole I. +11 more
core +5 more sources
Toward three-dimensional in vitro models to study neurovascular unit functions in health and disease [PDF]
Neural Regeneration Research, 2021 The high metabolic demands of the brain require an efficient vascular system to be coupled with neural activity to supply adequate nutrients and oxygen. This supply is coordinated by the action of neurons, glial and vascular cells, known collectively as ...
Tara M Caffrey +2 more
doaj +2 more sources
Construction and imaging of a neurovascular unit model
Neural Regeneration Research, 2022 In 2001, the concept of the neurovascular unit was introduced at the Stroke Progress Review Group meeting. The neurovascular unit is an important element of the health and disease status of blood vessels and nerves in the central nervous system.
Taiwei Dong +4 more
doaj +3 more sources
Neural Regeneration Research, 2019 Previous studies have shown that models of depression exhibit structural and functional changes to the neurovascular unit. Thus, we hypothesized that diabetes-related depression might be associated with damage to the hippocampal neurovascular unit.
Jian Liu +6 more
doaj +2 more sources
Ultrastructure of precapillary sphincters and the neurovascular unit
Vascular Biology, 2023 Neurons communicate with vasculature to regulate blood flow in the brain, a process maintained by the neurovascular unit (NVU). This interaction, termed neurovascular coupling, is believed to involve astrocytes or molecules capable of traversing the ...
Grubb, Søren
core +5 more sources
Fibrinogen and Neuroinflammation in the Neurovascular Unit in Stroke. [PDF]
J Inflamm ResYi Chen,1 Lu Han,1 De-Sheng Zhu,1,2 Yang-Tai Guan1,3 1Department of Neurology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, People’s Republic of China; 2Department of Neurology, Baoshan Branch, Renji Hospital ...
Chen Y, Han L, Zhu DS, Guan YT.
europepmc +5 more sources
Neurovascular Unit in Chronic Pain [PDF]
Mediators of Inflammation, 2013 Chronic pain is a debilitating condition with major socioeconomic impact, whose neurobiological basis is still not clear. An involvement of the neurovascular unit (NVU) has been recently proposed.
Beatrice Mihaela Radu +6 more
doaj +3 more sources
How does neurovascular unit dysfunction contribute to multiple sclerosis?
Neurobiology of Disease, 2023 Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system (CNS) and the most common non-traumatic cause of neurological disability in young adults.
Jake M. Cashion +2 more
doaj +2 more sources
Neurovascular Unit Dysfunction and Neurodegenerative Disorders [PDF]
Frontiers in Neuroscience, 2020 The neurovascular unit (NVU), composed of vascular cells, glial cells, and neurons, is the minimal functional unit of the brain. The NVU maintains integrity of the blood–brain barrier (BBB) and regulates supply of the cerebral blood flow (CBF), both of ...
Xing Yu, Caihong Ji, Anwen Shao
doaj +3 more sources
Subarachnoid Hemorrhage, Spreading Depolarizations and Impaired Neurovascular Coupling [PDF]
Stroke Research and Treatment, 2013 Aneurysmal subarachnoid hemorrhage (SAH) has devastating consequences on brain function including profound effects on communication between neurons and the vasculature leading to cerebral ischemia.
Masayo Koide +3 more
doaj +2 more sources