Results 261 to 270 of about 17,591 (285)

Ethanol modulates the neurovascular coupling

NeuroToxicology, 2013
Despite some evidence of the underlying molecular mechanisms the neuronal basis of ethanol-induced effects on the neurovascular coupling that forms the BOLD (blood oxygenation level dependent) signal is poorly understood. In a recent fMRI (functional magnetic resonance imaging) study monitoring ethanol-induced changes of the BOLD signal a reduction of ...
Michael, Luchtmann, Katja, Jachau, Daniela, Adolf, Friedrich-Wilhelm, Röhl, Sebastian, Baecke, Ralf, Lützkendorf, Charles, Müller, Johannes, Bernarding   +7 more
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Modeling of the Neurovascular Coupling in Epileptic Discharges

Brain Topography, 2011
Despite the interest in simultaneous EEG-fMRI studies of epileptic spikes, the link between epileptic discharges and their corresponding hemodynamic responses is poorly understood. In this context, biophysical models are promising tools for investigating the mechanisms underlying observed signals.
Voges, Nicole, Blanchard, Solenna, Wendling, Fabrice, David, Olivier, Benali, Habib, Papadopoulo, Théodore, Clerc, Maureen, Bénar, Christian   +7 more
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The contribution of astrocyte signalling to neurovascular coupling

Brain Research Reviews, 2010
The tight spatial and temporal coupling between neuronal activity and blood flow ensures that active brain regions receive an adequate supply of oxygen and energetic metabolites. There clearly is still an enormous amount of experimental and theoretical work to be done to unravel the precise mechanism of neurovascular coupling, but over the last decade ...
Carmignoto, Giorgio, GomezGonzalo, Marta
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Fractional dynamical model for neurovascular coupling

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2014
The neurovascular coupling is a key mechanism linking the neural activity to the hemodynamic behavior. Modeling of this coupling is very important to understand the brain function but it is at the same time very complex due to the complexity of the involved phenomena.
Zehor Belkhatir, Taous-Meriem Laleg-Kirati   +1 more
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The role of nitric oxide in neurovascular coupling

Journal of Theoretical Biology, 2016
Nitric oxide (NO) is a neurotransmitter known to act as a potent cerebral vasodilator. Its role in neurovascular coupling (NVC) is discussed controversially and one of the main unanswered questions is which cell type provides the governing source of NO for the regulation of vasodynamics.
Dormanns, K., Brown, R. G., David, T.
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Angiotensin and Neurovascular Coupling: Beyond Hypertension

Microcirculation, 2015
AbstractBrain homeostasis is dependent upon the constant perfusion of oxygen and nutrients through CBF. The mechanism responsible to couple CBF to neuronal activity is termed NVC. Ang II, a key player in hypertension, impairs NVC and has been found to be of significant importance in neurodegenerative diseases, such as AD. The presence of Ang II and its
Sherri, Bloch, Dima, Obari, Hélène, Girouard   +2 more
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Investigating static nonlinearities in neurovascular coupling

Magnetic Resonance Imaging, 2011
Many statistical models of coupling between time changes of the band-limited power of neural signals and functional magnetic resonance imaging Blood Oxygenation Level Dependent (BOLD) signal time changes rely on linear convolution. The effect of nonlinear behaviors in single-trial relationships between neural signals and BOLD responses is rarely tested
Logothetis, Nikos, Magri, Cesare, Logothetis, Nikos K., Panzeri, Stefano   +3 more
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Neurovascular Coupling During Spreading Depolarizations

2012
Injury depolarizations akin to spreading depression of Leão are important in the progression of tissue damage in ischemic stroke, intracranial hemorrhage, and trauma. Much of the research on injury depolarizations has been focused on their origins, electrophysiological mechanisms, and metabolic impact.
Ulrike, Hoffmann, Cenk, Ayata
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Metabolic Aspects of Neurovascular Coupling

1997
In the previous chapter it was demonstrated that functional neuroimaging relies on the coupling of neuronal activity and cerebral blood flow. What is the function of neurovascular coupling? Does it serve to provide a constant glucose or oxygen delivery to brain cells? Does it mainly regulate removal of tissue metabolites such as lactate?
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Modeling Secondary Messenger Pathways in Neurovascular Coupling

Bulletin of Mathematical Biology, 2013
Neurovascular coupling is the well-documented link between neural stimulation and constriction or dilation of the surrounding vasculature. Glial cells mediate this response via their unique anatomy, which connects neurons to arterioles. It is believed that calcium transients and the release of secondary messengers by these cells influence the vascular ...
Hadfield, James, Plank, Michael J., David, Tim   +2 more
openaire   +3 more sources