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Cell–cell Signaling in the Neurovascular Unit
Neurochemical Research, 2007Historically, the neuron has been the conceptual focus for almost all of neuroscience research. In recent years, however, the concept of the neurovascular unit has emerged as a new paradigm for investigating both physiology and pathology in the CNS. This concept proposes that a purely neurocentric focus is not sufficient, and emphasizes that all cell ...
Josephine, Lok +6 more
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Proteomes and Biomarkers of the Neurovascular Unit
2017Brain vessels display a distinct phenotype that includes tight junctions and barrier properties of brain endothelial cells, as well as their close association with glial cells and neurons that enable tight coupling of blood flow with brain tissue energy demand.
Haqqani, A. S., Stanimirovic, D. B.
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RNA methylation and neurovascular unit remodeling.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2021RNA methylation is of great significance in the regulation of gene expression, among which the more important methylation modifiers are N6-methyladenosine (m6A) and 5-methylcytosine (m5C). The methylation process is mainly regulated by 3 kinds of proteins: methyltransferase, demethylase, and reader.
Xinyi, Lü +4 more
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Neurovascular unit impairment in iron deficiency anemia
NeuroscienceIron is one of the crucial elements for CNS development and function and its deficiency (ID) is the most common worldwide nutrient deficit in the world. Iron deficiency anemia (IDA) in pregnant women and infants is a worldwide health problem due to its high prevalence and its irreversible long-lasting effects on brain development.
Eugenia Isasi, Silvia Olivera-Bravo
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The Blood-Brain Barrier/Neurovascular Unit in Health and Disease
Pharmacological Reviews, 2005B. Hawkins, T. Davis
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The neurovascular unit and systemic biology in stroke — implications for translation and treatment
Nature Reviews Neurology, 2022S. Tiedt +5 more
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In-vitro models review - neurovascular unit [PDF]
Kocikowska, Olga +2 more
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