Results 81 to 90 of about 3,790,471 (295)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Nonparametric Estimation of Risk-Neutral Densities [PDF]

open access: yes
This chapter deals with nonparametric estimation of the risk neutral density. We present three different approaches which do not require parametric functional assumptions on the underlying asset price dynamics nor on the distributional form of the risk ...
Wolfgang Karl Härdle   +2 more
core  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The forecasting performance of German stock option densities [PDF]

open access: yes
In this paper the authors estimate risk-neutral densities (RND) for the largest euro-area stock market (the index of which is the German DAX), reporting their statistical properties, and evaluating their forecasting performance.
Ben Craig   +3 more
core   +2 more sources

Neutral Bay.

open access: yes, 1886
Advertisements on preliminary and final leaves.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map-lfsp1703. The land for sale was "the extensive property held by the late Mr. Patrick Hayes"

core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Crash risk and risk neutral densities

open access: yesJournal of Empirical Finance, 2018
“Crash risk” has been one of the major focuses in the recent asset pricing literature. Motivated by the recent literature that suggests an increase in crash risk since Fall 2008 and the recent troubles in the Euro zone, we use EUR/USD FX options for January 2, 2008 to March 18, 2015 to study option-implied risk-neutral densities (RND). We find that RND,
Ren-Raw Chen   +2 more
openaire   +3 more sources

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

Predicting global thermospheric neutral density during periods with high geomagnetic activity. [PDF]

open access: yesSci Rep, 2023
Forootan E   +5 more
europepmc   +1 more source

Testing the Forecasting Performance of Ibex 35 Option-implied Risk-neutral Densities [PDF]

open access: yes
Published also as: Documento de Trabajo Banco de España 0504/2005.risk-neutral densities, forecasting ...
Rubio Irigoyen, Gonzalo   +2 more
core  

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