Results 41 to 50 of about 198,977 (286)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Functional differential equations of third order

Electronic Journal of Differential Equations, 2005
In this paper, we consider the third-order neutral functional differential equation with distributed deviating arguments. We give sufficient conditions for the oscillatory behavior of this functional differential equation.
Tuncay Candan, Rajbir S. Dahiya
doaj  

Optimal Control for Functional-Differential Equation of Neutral Type in BanachТ‘Т‘ Spaces

Journal of Optimization, Differential Equations and Their Applications
This paper examines an optimal control problem for a class of neutral-type functional-differential equations in Banach spaces, where the control objective relates to the boundary of the domain. Sufficient conditions on the coefficients are established to
O. V. Perehuda, O. M. Stanzhytskiy, T. V. Klimchuk, M. N. Ospanov   +3 more
doaj   +1 more source

Stability of Nonlinear Neutral Stochastic Functional Differential Equations

Journal of Applied Mathematics, 2010
Neutral stochastic functional differential equations (NSFDEs) have recently been studied intensively. The well‐known conditions imposed for the existence and uniqueness and exponential stability of the global solution are the local Lipschitz condition and the linear growth condition.
Xue, Minggao, Zhou, Shaobo, Hu, Shigeng
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

On Neutral Functional–Differential Equations with Proportional Delays

Journal of Mathematical Analysis and Applications, 1997
The paper deals with the well-posedness of the initial value problem for the neutral functional-differential equation \[ y'(t)= ay(t)+ \sum_{i=1}^\infty b_iy(q_it)+ \sum_{i=1}^\infty cy'(p_it), \qquad t>0, \quad y(0)=y_0 \] and the asymptotic behaviour of its solutions.
Iserles, Arieh, Liu, Yunkang
openaire   +2 more sources

Statistical mechanics approach to some problems in conformal geometry

, 2000
A weak law of large numbers is established for a sequence of systems of N classical point particles with logarithmic pair potential in $\bbR^n$, or $\bbS^n$, $n\in \bbN$, which are distributed according to the configurational microcanonical measure ...
Aubin, Aviles, Beckner, Billingsley, Branson, Branson, Branson, Caglioti, Caglioti, Campbell, Carlen, Chang, Chang, Chang, Chang, Chanillo, Chanillo, Chen, Chen, Cheng, Cheng, Chou, de Finetti, Diaconis, Dynkin, Eyink, Fröhlich, Han, Hewitt, Joyce, Kazdan, Kida, Kiessling, Kiessling, Kiessling, Kiessling, Lin, Liouville, Lundgren, Marchioro, McOwen, Messer, Michael K.-H. Kiessling, Montgomery, Montgomery, Moser, Moser, Ni, O'Neil, Onofri, Onsager, Osserman, Poincaré, Pointin, Ramsey, Saff, Sattinger, Struik, Trudinger   +58 more
core   +2 more sources

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

S-asymptotically omega-periodic solutions for abstract neutral differential equations

Electronic Journal of Differential Equations, 2015
In this article we study the existence of S-asymptotically omega-periodic solutions for abstract neutral functional differential equations recently, introduced in the literature.
Michelle Pierri, Donal O'Regan
doaj  

Periodic solutions of convex neutral functional differential equations

Tohoku Mathematical Journal, 2000
In this paper, the authors study the existence of periodic solutions to neutral differential equations. It is proved that for convex neutral functional-differential equations of \(D\)-operator type with finite (or infinite) delay and hyperneutral functional-differential equations with finite delay the problem of the existence of periodic solutions is ...
Fan, Meng, Wang, Ke
openaire   +2 more sources