Results 51 to 60 of about 203,110 (287)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

S-asymptotically omega-periodic solutions for abstract neutral differential equations

Electronic Journal of Differential Equations, 2015
In this article we study the existence of S-asymptotically omega-periodic solutions for abstract neutral functional differential equations recently, introduced in the literature.
Michelle Pierri, Donal O'Regan
doaj  

Bilayer Membrane in Confined Geometry: Interlayer Slide and Steric Repulsion

, 2004
We derived free energy functional of a bilayer lipid membrane from the first principles of elasticity theory. The model explicitly includes position-dependent mutual slide of monolayers and bending deformation.
A. Ben-Shaul, A. Yeung, E. Evans, E. I. Kats, E. I. Kats, F. Brochard, F. C. MacKintosh, H. Kleinert, L. D. Landau, M. Kraus, S. A. Safran, U. Seifert, U. Seifert, U. Seifert, W. Helfrich, W. Helfrich   +15 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Estimation of Solutions of Differential Systems with Delayed Argument of Neutral Type [PDF]

, 2012
Tato disertační práce pojednává o řešení diferenciálních rovnic a systémů diferenciálních rovnic. Hlavní pozornost je věnována asymptotickým vlastnostem rovnic se zpožděním a systémů rovnic se zpožděním.
Baštincová, Alena
core  

Statistical mechanics approach to some problems in conformal geometry

, 2000
A weak law of large numbers is established for a sequence of systems of N classical point particles with logarithmic pair potential in $\bbR^n$, or $\bbS^n$, $n\in \bbN$, which are distributed according to the configurational microcanonical measure ...
Aubin, Aviles, Beckner, Billingsley, Branson, Branson, Branson, Caglioti, Caglioti, Campbell, Carlen, Chang, Chang, Chang, Chang, Chanillo, Chanillo, Chen, Chen, Cheng, Cheng, Chou, de Finetti, Diaconis, Dynkin, Eyink, Fröhlich, Han, Hewitt, Joyce, Kazdan, Kida, Kiessling, Kiessling, Kiessling, Kiessling, Lin, Liouville, Lundgren, Marchioro, McOwen, Messer, Michael K.-H. Kiessling, Montgomery, Montgomery, Moser, Moser, Ni, O'Neil, Onofri, Onsager, Osserman, Poincaré, Pointin, Ramsey, Saff, Sattinger, Struik, Trudinger   +58 more
core   +2 more sources

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Generalized Mean Square Exponential Stability for Stochastic Functional Differential Equations

Mathematics
This work focuses on a class of stochastic functional differential equations and neutral stochastic differential functional equations. By using a new approach, some sufficient conditions are obtained to guarantee the generalized mean square exponential ...
Tianyu He, Zhi Li, Tianquan Feng
doaj   +1 more source

Asymptotic properties of the spectrum of neutral delay differential equations

, 2009
Spectral properties and transition to instability in neutral delay differential equations are investigated in the limit of large delay. An approximation of the upper boundary of stability is found and compared to an analytically derived exact stability ...
Blyuss, K. B., Hoevel, P., Kyrychko, Y. N., Schoell, E.   +3 more
core   +1 more source