Results 61 to 70 of about 1,396 (250)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Bogdanov-Takens bifurcation for neutral functional differential equations

Electronic Journal of Differential Equations, 2013
In this article, we consider a class of neutral functional differential equations (NFDEs). First, some feasible assumptions and algorithms are given for the determination of Bogdanov-Takens (B-T) singularity.
Jianzhi Cao, Rong Yuan
doaj  

Unique solvability
 of second order functional differential equations with non-local
 boundary conditions

Electronic Journal of Qualitative Theory of Differential Equations, 2012
Some general conditions sufficient for unique solvability of the
 boundary-value problem for a system of linear functional
 differential equations of the second order are established.
Natalia Dilna
doaj   +1 more source

On a class of first order nonlinear functional differential equations of neutral type [PDF]

, 1987
Consider the neutral differential equation ddt [y(t) + py(t − τ)] + qy(t − σ) = 0, t ≧ t0 (∗) where p, q, τ, and σ are real numbers. Then a necessary and sufficient condition for the oscillation of (∗) is that the characteristic equation λ + pλe−λτ + qe ...
Ladas, G, Meimaridou, A, Jaroš, Jaroslav, Kusano, Takaŝi, Grove, E.A   +4 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Almost Automorphic Mild Solutions to Neutral Parabolic Nonautonomous Evolution Equations with Nondense Domain

Discrete Dynamics in Nature and Society, 2013
Combining the exponential dichotomy of evolution family, composition theorems for almost automorphic functions with Banach fixed point theorem, we establish new existence and uniqueness theorems for almost automorphic mild solutions to neutral parabolic ...
Zhanrong Hu, Zhen Jin
doaj   +1 more source

Periodic Solution for a Kind of Third-Order Neutral-Type Differential Equation

Journal of Function Spaces, 2023
In this paper, we investigate a class of a third-order neutral-type differential equation with time-varying delays. Some sufficient conditions on the existence of a periodic solution are established for the considered system.
Axiu Shu, Bo Du
doaj   +1 more source

Investigation of the Oscillatory Properties of Solutions of Differential Equations Using Kneser-Type Criteria

Axioms, 2023
This study investigates the oscillatory properties of a fourth-order delay functional differential equation. This study’s methodology is built around two key tenets.
Yousef Alnafisah, Osama Moaaz
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source