Results 61 to 70 of about 5,969,124 (243)

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Stray voltage symptoms common in dairy cattle eliminated by on-farm neutral isolation [PDF]

, 2000
Plan BDairy farmers with stray voltage symptoms in their cattle often spend thousands of dollars to do neutral isolation, which isolates the primary neutral of the electricity provider from the farm neutral to suppress stray voltage from off-farm sources
Nackers, Martin
core  

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Low Frequency Harmonics Reduction Discontinuous PWM Strategy With Active Neutral Point Voltage Control for Neutral Point Clamped Three-Level Inverter

IEEE Access, 2020
The traditional discontinuous pulse width modulation (DPWM) strategy is very suitable for reducing the switching losses of three-level inverter (TLI).
Weidong Jiang, Qingyan Zhang, Ma Mingna, Xinmei Huang   +3 more
doaj   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

A VSC transmission system using flying capacitor multilevel converters and selective harmonic elimination pWM control [PDF]

, 2005
A transmission system based on voltage-source three-level flying capacitor (FC) multilevel converters with selective harmonic elimination pulse-width modulation (SHE-PWM) control is presented in this paper.
Lie Xu, Agelidis, V.G., V.G. Agelidis, Xu, L.   +3 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

A modified neutral-point balancing space vector modulation technique for three-level neutral point clamped converters in high speed drives [PDF]

, 2018
This paper describes a high performance neutral point voltage balancing technique for a Neutral point clamped (NPC) Converter. Conventional neutral point voltage balancing methods do not function well under low power factor, low pulse ratio and near ...
Li, Chen, Yang, Tao, Bozhko, Serhiy, Wheeler, Patrick, Tao Yang, Lo Calzo, Giovanni, Gerada, Chris, Ponggorn Kulsangcharoen, Chen Li, Giovanni Lo Calzo, Patrick Wheeler, Kulsangcharoen, Ponggorn, Christopher Gerada, Serhiy Bozhko, Gerada, Christopher   +14 more
core   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Voltage Balancing Control of Hybrid Stacked Multicell Converters Based on Modified Phase-Shifted PWM

IEEE Access, 2019
The hybrid stacked multicell converter (HSMC) is a competitive converter in the low-voltage high-efficiency applications. Proper modulation and voltage balancing control are important for the operation of the HSMC, which may ensure the HSMC to obtain ...
Jianzhong Zhang, Shuai Xu, Xing Hu, Yaodong Zhu   +3 more
doaj   +1 more source