KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Temporary Cabinet Foreign Policy: of Non – alignment to Neither West Nor East Principle [PDF]
Temporary Cabinet Foreign Policy: of Non – alignment to Neither West Nor East Principle Seyd Hasan Mir Fakhraei* (Received:2014/June/14 – Accept: 2014/Octobr/27) Abstract Foreign policy of the Bazargan cabinet is one of the most controversial ...
seyyed hassan Mirfakhrayi
doaj
This paper first sets out a framework for understanding network neutrality, by organizing the various issues raised in the course of the network neutrality debate. Secondly, recent US legal and regulatory initiatives are briefly reviewed. Thirdly, the situation under EU law is surveyed.
openaire +3 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
NETRALITAS POLITIK KIAI DALAM PERSPEKTIF TEORI INTERAKSI SIMBOLIK
The researcher examines the neutrality of the Kiai in the political year due to the existence of one of the candidates for the vice president who participated in the 2019 election is a great Ulama.
Nurma Yuwita +2 more
doaj +1 more source
The Net Neutrality Debate: Twenty Five Years after United States v. AT&T and 120 Years after the Act to Regulate Commerce [PDF]
Apparent ignorance of more than a century of economic history now threatens the competitive constitution of the Internet under the guise of "net neutrality." Net neutrality is a slogan that stands for the proposition that the Internet and physical means ...
Owen, Bruce M.
core +1 more source
Power-Law Distributions in a Two-sided Market and Net Neutrality
"Net neutrality" often refers to the policy dictating that an Internet service provider (ISP) cannot charge content providers (CPs) for delivering their content to consumers. Many past quantitative models designed to determine whether net neutrality is a
A Odlyzko +15 more
core +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Assessing the Current State of Net Neutrality and Exploring Solutions in Creating and Maintaining Open, Available, and Innovative Internet and Broadband Services [PDF]
This article examines the current state of net neutrality regulation in the United States. Debates surrounding net neutrality are varied and layered. They include legal questions regarding how the internet should be classified under existing statutes ...
Troiano, Robbie
core +1 more source

