Results 71 to 80 of about 266,471 (305)

Deep Learning-Enabled Flexible PVA/CNPs Hydrogel Film Sensor for Abdominal Respiration Monitoring

open access: yesGels
In this study, a flexible hydrogel film sensor based on the intermixing of poly(vinyl alcohol) (PVA) and biomass-derived carbon nanoparticles (CNPs) was prepared and microstructures were constructed by replicating sandpaper templates on its surface.
Chengcheng Peng   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Characterization of a Second Bovine Rotavirus Serotype [PDF]

open access: yes, 1987
Bovine rotavirus (BRV) V 1005 was characterized by two-way cross-neutralization tests as a second serotype of BRV. Virions and inner shell particles of 65 nm and 55 nm diameter respectively, and empty capsids of 65 nm and 55 nm diameter were separated by
Fryder, V.   +4 more
core   +2 more sources

Stimulus-Responsive Afterglow Carbon Dots from Internal Mechanism to Potential Application

open access: yesNanomaterials
Stimulus-responsive afterglow materials refer to a class of substances whose afterglow characteristics alter under external stimuli, showing considerable potential for advanced applications in anti-counterfeiting, optoelectronic displays, chemical ...
Chongye Xia   +5 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Understanding the interplay between HIV-1 diversity, humoral immune responses and viral fitness [PDF]

open access: yes, 2014
Includes bibliographical references.HIV-1 antibody dependent cell cytotoxicity (ADCC) and neutralizing antibody (nAb) responses are both thought to be important responses to elicit through vaccination.
Bandawe, Gama Petulo
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Accelerated Development of Vapor Deposition Technology for Efficient Perovskite Solar Cells via Accurate and Practical Machine Learning Tools

open access: yesAdvanced Science
The development of vapor deposition technology will accelerate the process of perovskite solar cells (PSCs) moving from laboratory scale to industrialization. However, the multi‐dimensional and complex parameter space will inevitably increase the cost of
Long Luo   +8 more
doaj   +1 more source

Viral neutralization studies.

open access: yes, 2022
The results of the viral variant testing. Heat map represents activity as measured by the average ratio of the mutation IC50/wild type (D614G). Ratios are provided in the Figures.
Kamaljit Bajwa (12769627)   +17 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

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