Results 61 to 70 of about 404,578 (298)

Accelerated Development of Vapor Deposition Technology for Efficient Perovskite Solar Cells via Accurate and Practical Machine Learning Tools

open access: yesAdvanced Science
The development of vapor deposition technology will accelerate the process of perovskite solar cells (PSCs) moving from laboratory scale to industrialization. However, the multi‐dimensional and complex parameter space will inevitably increase the cost of
Long Luo   +8 more
doaj   +1 more source

Trace nano-Ti addition for graphene nanoplatelets/copper composites to simultaneously enhance strength-ductility and wear resistance

open access: yesJournal of Materials Research and Technology
Graphene nanoplatelets (GNPs)/copper composites containing nano-Ti addition were prepared using the vacuum hot-pressing sintering process. The effect of Nano-Ti on microstructure and mechanical properties of GNPs/copper composite was investigated. Before
Xinjiang Zhang   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Insights into the synergistic effect between nickel and molybdenum for catalyzing urea electrooxidation

open access: yesCarbon Neutralization, 2022
The efficiency of many clean technologies, such as urea fuel cells, hydrogen production from urea‐containing water splitting, and sewage treatment, and so forth, is restricted due to the sluggish kinetics of the urea oxygen reaction (UOR).
Jiaqi Wang   +7 more
doaj   +1 more source

Emergent neutrality

open access: yesTrends in Ecology & Evolution, 2006
Community ecology is in a current state of creative ferment, stimulated by the development of neutral models of community organization. Here, I reflect on recent papers by Scheffer and van Nes, and by Gravel et al., which illuminate how neutrality can emerge from ecological and evolutionary processes, thus suggesting ways to unify neutral and niche ...
Department of Zoology, University of Florida, Gainesville, FL 32605, USA ( host institution )   +1 more
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Morphology and structure of lead‐free CuSb‐based double perovskites for photocatalytic CO2 reduction

open access: yesCarbon Neutralization, 2022
Lead‐free halide double perovskites (DPs) have attracted great attention due to their stability, nontoxicity, and good photophysical properties. Herein, environmentally friendly small‐bandgap Cs2CuSbCl6 and Cs4CuSb2Cl12 DPs microcrystals (MCs) are ...
Daofu Wu   +8 more
doaj   +1 more source

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