Results 41 to 50 of about 266,471 (305)

Llama-Derived Single Domain Antibodies to Build Multivalent, Superpotent and Broadened Neutralizing Anti-Viral Molecules [PDF]

, 2011
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (
Schepens, B, Temperton, Nigel J., M. Koenders, C. Theo Verrips, Schillemans, J, Ibanez, Lorena Itatı, J. Melero, de Haard, HJ, Verrips, C. Theo, S. Van Gucht, C.T. Verrips, Michael Saunders, Bert Schepens, Temperton, Nigel J, Ibanez, Lorena, Koenders, M, Melero, Jose A., Schepens Bert, de Haard, Hans J, Vanlandschoot, P, Steven Van Gucht, Gonzalez-Pajuelo Maria, Van Gucht, S, Xavier Saelens, Vanlandschoot Peter, Anna Hultberg, B. Schepens, Gonzalez-Pajuelo, Maria, Schillemans Joris, Koenders, Mireille, Nigel J. Temperton, Saunders Michael, Melero José A., de Haard, Hans J., Schillemans, Joris, Ibañez Lorena Itatí, de Haard Hans J., Temperton Nigel J., Ibañez,, Lorena Itatí, H.J. de Haard, Robin A. Weiss, Hultberg, A, Schepens, Bert, C Theo Verrips, N.J. Temperton, Ibanez, LI, Van Gucht, Steven, Verrips, Theo, Maria Gonzalez-Pajuelo, L.I. Ibanez, Rosseels Valérie, José A Melero, Hans J de Haard, Mireille Koenders, Hultberg Anna, Weiss, RA, Saelens Xavier, Saunders, Michael, R.A. Weiss, Weiss Robin A., Saelens, Xavier, Hans J. de Haard, Lorena Itatí Ibañez, A. Hultberg, Gonzalez-Pajuelo, M, Weiss, Robin A., Saelens, X, Joris Schillemans, Verrips, CT, Peter Vanlandschoot, Van Gucht Steven, M. Saunders, Valérie Rosseels, V. Rosseels, Koenders Mireille, Robin A Weiss, P. Vanlandschoot, Rosseels, V, José A. Melero, Hultberg, Anna, M. Gonzalez-Pajuelo, Rosseels, Valerie, J. Schillemans, Ibañez, Lorena Itatí, Melero, Jose Antonio, Vanlandschoot, Peter, Weiss, Robin A, Saunders, M, Nigel J Temperton, X. Saelens, Melero, José A, Verrips C. Theo, Temperton, NJ, Melero, JA, Verrips, C Theo   +94 more
core   +1 more source

Study on friction behavior and wear resistance mechanism of different screw materials during homogenization of LFP/NCM battery slurries

Journal of Materials Research and Technology
SUS304 steel is widely employed as the core component material in battery slurry homogenization equipment. However, due to its insufficient hardness and poor resistance to plastic deformation, severe abrasive wear and oxidative corrosive wear tend to ...
Xiangli Wen, Mingkun Bi, Lvzhou Li, Jianning Ding   +3 more
doaj   +1 more source

Research on the Influence of the Interfacial Properties Between a Cu3BiS3 Film and an InxCd1−xS Buffer Layer for Photoelectrochemical Water Splitting

Advanced Science, 2022
The ternary compound photovoltaic semiconductor Cu3BiS3 thin film‐based photoelectrode demonstrates a quite promising potential for photoelectrochemical hydrogen evolution.
Xiaomin Wu, Weidong Zhao, Yucheng Hu, Guohong Xiao, Huanyang Ni, Shigeru Ikeda, Yunhau Ng, Feng Jiang   +7 more
doaj   +1 more source

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

, 2022
The emergence of the SARS-CoV-2 variant of concern Omicron (Pango lineage B.1.1.529), first identified in Botswana and South Africa, may compromise vaccine effectiveness and lead to re-infections1.
Tegally, Houriiyah, Smith, Muneerah, Bernstein, Mallory, Cele, Sandile, Cromer, Deborah, Amoako, Daniel G, Lustig, Gila, Jackson, Laurelle, Scheepers, Cathrine, San, James Emmanuel, Archary, Derseree, Moyo-Gwete, Thandeka, Khan, Khadija, Khoury, David S, Karim, Farina, et al.   +15 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Fluorine-free acetonitrile-based electrolytes with anion-reinforced solvation chemistry for sustainable sodium-ion full batteries

Nature Communications
Acetonitrile-based electrolytes have garnered significant attention for sodium-ion batteries due to their high ionic conductivity and favorable oxidation resistance.
Xu Xu, Jian Chen, Zhuo Yang, Zhiming Zhou, Xiaosa Zhang, Xinhui Zeng, Yun Wan, Xiaomin Chen, Wenxi Kuang, Xiaoyan Shi, Lingling Zhang, Xunzhu Zhou, Shulei Chou, Lin Li   +13 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Neutralization-Induced Self-Assembly of Cellulose Oligomers into Antibiofouling Crystalline Nanoribbon Networks in Complex Mixtures

, 2020
Molecular self-assembly in solutions is a powerful strategy for fabricating functional architectures. Various bio­(macro)­molecules have been used as self-assembly components. However, structural polysaccharides, such as cellulose and chitin, have rarely
Takeshi Serizawa (1821394), Takeshi Serizawa, Toshiki Sawada, Tohru Maeda, Tohru Maeda (8441349), Toshiki Sawada (1821388)   +5 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Cattle develop neutralizing antibodies to rotavirus serotypes which could not be isolated from faeces of symptomatic calves [PDF]

, 1991
Neutralizing antibodies against 10 serotypes of rotavirus were measured in sera from different age groups of German cattle. Only five of 143 sera did not neutralize heterologous serotypes.
Sidoti, Josette, Eichhorn, Werner, Snodgrass, David, Büssow, Harald, Rohwedder, Angela   +4 more
core   +1 more source