Human monoclonal antibody combination against SARS coronavirus : synergy and coverage of escape mutants [PDF]
Background: Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible.
Peiris, Joseph S. M. +73 more
core +1 more source
Evaluating the neutralizing antibody response to HIV-1 membrane proximal external regional; Implications for vaccine design [PDF]
Includes bibliographical references.Inducing broadly neutralizing antibodies targeting the HIV-1 envelope is thought to be crucial for developing an effective vaccine.
Jacob, Rajesh Abraham
core +1 more source
Daniel Berthelot. Part II. Contribution to electrolytic solutions
Daniel Berthelot (1865-1927) used the electrical conductivity method to carry on fundamental research on the chemical equilibrium present in highly diluted electrolyte solutions, using the electrical conductivity method. In this way he was able to follow
Jaime Wisniak
doaj +1 more source
Theoretical study of the I++ I- mutual neutralization reaction [PDF]
We have computed the cross sections of the mutual neutralization reaction between I+ and I- for a collision energy varying from 0.001 eV to 50 eV. These cross sections were obtained using the adiabatic potential energy curves of the I2 system computed ...
Sisourat, Nicolas +6 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Metal-free porphyrin with good planarity is beneficial to π−π stack interactions, which promotes electron coupling and the separation and transfer of photogenerated carriers.
Jinrong Lu +4 more
doaj +1 more source
Sequence-based prediction for vaccine strain selection and identification of antigenic variability in foot-and-mouth disease virus [PDF]
Identifying when past exposure to an infectious disease will protect against newly emerging strains is central to understanding the spread and the severity of epidemics, but the prediction of viral cross-protection remains an important unsolved problem ...
Reeve Richard +64 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Waste-concrete recycling processes using wet-based crushing methods inevitably generate a large amount of alkaline concrete sludge, as well as wastewater, which contains abundant Ca ions. The Ca-rich alkaline wastewater must then be neutralized for reuse
Jongchan Yoo, Heeyoung Shin, Sangwoo Ji
doaj +1 more source
Empirical modeling the ultrasound-assisted base-catalyzed sunflower oil methanolysis kinetics [PDF]
The ultrasound-assisted sunflower oil methanolysis catalyzed by KOH was studied to define a simple empirical kinetic model useful for reactor design without complex computation.
Avramović Jelena M. +4 more
doaj +1 more source

