Results 41 to 50 of about 5,673,625 (341)

Evaluation of two eco-friendly neutralizers for a spectrum of tissue fixatives for biomedical applications. [PDF]

, 2018
Formaldehyde is a widely used aldehyde in biomedical applications, including tissue fixation. It is this same fixative property that can result in toxicity if aldehydes are improperly discarded.
Carmichael, Stanley Thomas, Prakash, Roshini   +1 more
core  

TOXIN-ANTITOXIN REACTION WITHOUT NEUTRALIZATION [PDF]

Journal of Experimental Medicine, 1932
1. Collodion particles adsorb diphtheria or tetanus or botulinus toxins. These toxins are retained on the particles when washed but are at least in part released in the animal. 2. The adsorbed toxins are neutralized by adsorption of the corresponding antitoxins but are unaffected by other serums. 3.
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Tuning the Supramolecular Structures of Metal-Free Porphyrin via Surfactant Assisted Self-Assembly to Enhance Photocatalytic Performance

Nanomaterials, 2019
Metal-free porphyrin with good planarity is beneficial to π−π stack interactions, which promotes electron coupling and the separation and transfer of photogenerated carriers.
Jinrong Lu, Zihan Li, Weijia An, Li Liu, Wenquan Cui   +4 more
doaj   +1 more source

Konfirmatori faktor analisis kepuasan kerja dosen [PDF]

, 2018
The University is one of the places to improve the quality of human resources. The development of education at the University of Batam city in particular has involved many parties, namely professors, the University, the community and other educational ...
Hazriyanto, H, Ibrahim, Badaruddin
core  

Cattle develop neutralizing antibodies to rotavirus serotypes which could not be isolated from faeces of symptomatic calves [PDF]

, 1991
Neutralizing antibodies against 10 serotypes of rotavirus were measured in sera from different age groups of German cattle. Only five of 143 sera did not neutralize heterologous serotypes.
Büssow, Harald, Eichhorn, Werner, Rohwedder, Angela, Sidoti, Josette, Snodgrass, David   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Assessment of the ability of SARS-CoV-2 strains of genetic variants B.1.1 and JN.1 to evade neutralizing antibodies from 2020 and 2023 convalescent patients

Инфекция и иммунитет
Introduction. The SARS-CoV-2 virus is a highly variable pathogen accounted for by random mutations leading to the emergence of new genetic variants. Natural selection of SARS-CoV-2 variants is, among other things, the result of population level immunity ...
Stepan A. Pyankov, A. V. Zaykovskaya, A. V. Rybel, S. A. Bodnev, O. V. Pyankov   +4 more
doaj   +1 more source

Dickkopf 1 impairs the tumor response to PD-1 blockade by inactivating CD8+ T cells in deficient mismatch repair colorectal cancer

Journal for ImmunoTherapy of Cancer, 2021
Background Dickkopf 1 (DKK1) is associated with tumor progression. However, whether DKK1 influences the tumor response to programmed cell death protein 1 (PD-1) blockade in colorectal cancers (CRCs) with deficient mismatch repair (dMMR) or microsatellite
Yuan Li, Jian Zheng, Zhizhong Pan, Penghui Zhou, Guochen Liu, Wu Jiang, Pei-Rong Ding, Zexian Liu, Qiaoqi Sui, Dingxin Liu, Jinghua Tang, Lingheng Kong, Kai Han, Leen Liao, Qingjian Ou, Binyi Xiao, Yihong Ling, Jiewei Chen, Zhixiang Zuo   +18 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source