Results 51 to 60 of about 100,947 (311)

ENERGETIC BIOCIDAL MATERIALS AND SPORE NEUTRALIZATION [PDF]

open access: yes, 2015
The objective of this dissertation is to explore a more accurate and versatile approach to investigating the neutralization of spores suffered from ultrafast heating and biocide based stresses, and further to explore and understand novel methods to ...
Zhou, Wenbo
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Process optimization using response surface design for diacylglycerol synthesis from palm fatty acid distillate by enzymatic esterification [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2013
Diacylglycerols (DAG) were synthesized by lipase-catalyzed esterification of glycerol with palm fatty acid distillate(PFAD). Lipase from Rhizomucor miehei was used and the reaction was carried out at 45°C.
Songsri Santisawadi   +3 more
doaj  

Integrating Treatment of Neutralization with Sulfidic Natural Water (SNW) to Capture Dissolved Copper (Cu2+) from Acid Mine Drainage (AMD) at Batu Hijau Site, Sumbawa Island Indonesia

open access: yesIndonesian Journal of Chemistry, 2018
The overall objectives of the research were (1) to study the capability of sodium hydrosulfide (NaHS) and sulfidic natural water (SNW) of Sebau in recovery of Cu2+, (2) to investigate the potency of integrating treatments of neutralization with ...
Surya Hadi   +3 more
doaj   +1 more source

Controllable Extinction Property of Au/SiO<sub>2</sub> Nanocomposite Induced by Neutralization Reaction Time

open access: yes, 2011
The Au/SiO2nanocomposite was produced using surface active agent P123, and its optical absorption spectra was measured by spectrophotometer. It was found that the intensity of absorption peak was strengthened and underwent a red-shift as the ...
Sheng Li Chang   +5 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Phase transformations kinetics in barium titanate synthesis by mechanochemical processing [PDF]

open access: yesHemijska Industrija
This article presents the research results on a dry mechanochemical synthesis of barium titanate at a low temperature in which the reaction model and kinetics were determined during the activation of a powder mixture of titanium dioxide and barium oxide.
Đorđević Nataša G.   +4 more
doaj   +1 more source

Complement-Mediated Neutralization of Canine Distemper Virus In Vitro: Cross-Reaction between Vaccine Onderstepoort and Field KDK-1 Strains with Different Hemagglutinin Gene Characteristics

open access: yes, 2002
The properties of neutralization of antigens of canine distemper virus Onderstepoort and a recent field isolate, KDK-1, were investigated with strain-specific dog sera.
Ken Maeda   +3 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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