Immuno-Colorimetric Neutralization Test: A Surrogate for Widely Used Plaque Reduction Neutralization Tests in Public Health Virology [PDF]
Since their first documentation in 1952, plaque reduction neutralization tests (PRNTs) have become the choice of test for the measurement of neutralizing antibodies against a particular virus.
Sunil R. Vaidya
doaj +2 more sources
Body Temperature Drop as a Humane Endpoint in Snake Venom-Lethality Neutralization Tests [PDF]
Snake venom neutralization potency tests are required for quality control assessment by manufacturers and regulatory authorities. These assays require the use of large numbers of mice that manifest severe signs associated with pain and distress and long ...
Rosa De Jesus +7 more
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Limited Antibodies to Henipaviruses Detected Among Nigerian Horses Using Pseudotyped Virus Neutralization Tests [PDF]
The Hendra virus (HeV; Henipavirus hendraense) and Nipah virus (NiV; Henipavirus nipahense), members of the genus Henipavirus, are high-consequence pathogens that have caused multiple zoonotic outbreaks with high mortality.
Kitty Donnelly +5 more
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Paper-Based Biosensors for Monitoring Binding, Blocking, and Surrogate Neutralizing Antibody Responses Against Viral Infections [PDF]
Virus-specific antibody responses, including binding antibodies and neutralizing antibodies (nAbs), are important indicators of antiviral immune status after infection or immunization.
Yiren Yin +7 more
doaj +2 more sources
Reconciliation of titer differences between SARS-CoV-2 neutralizing antibody assays [PDF]
SARS-CoV-2 antibody neutralization is a correlate of protection for COVID-19 and has been used to guide public health decisions. However, there is no standard neutralization assay, and absolute titers differ between assays.
Eva Stadler +6 more
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Antibody Production after COVID-19 Vaccination in Patients with Inborn Errors of Immunity [PDF]
Background: Few studies have evaluated COVID-19 vaccine efficacy in patients with inborn errors of immunity (IEI).Objective: To evaluate the levels of antibody (Ab) production and function after COVID-19 vaccination in IEI patients with phagocytic ...
Maryam Nourizadeh +6 more
doaj +1 more source
Evaluation of Two Serological Assays for Diagnosing Zika Virus Infection
Zika virus (ZIKV) emerged and spread rapidly in South American countries during 2015. Efforts to diagnose ZIKV infection using serological tools were challenging in dengue-endemic areas because of antigenic similarities between both viruses.
Steev Loyola +7 more
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SARS-CoV-2–Specific Antibodies in Domestic Cats during First COVID-19 Wave, Europe
We conducted a severe acute respiratory syndrome coronavirus 2 antibody seroprevalence study among >2,000 domestic cats from 4 countries during the first coronavirus disease wave in Europe.
Claudia Schulz +10 more
doaj +1 more source
Estimating neutralizing activity in vaccinees is crucial for predicting the protective effect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Beomki Lee +22 more
doaj +1 more source
Dengue is an important public health problem worldwide, with India contributing nearly a third of global dengue disease burden. The measurement of neutralizing antibody responses is critical for understanding dengue pathophysiology, vaccine development ...
Pragati Sharma +5 more
doaj +1 more source

