Results 41 to 50 of about 146,246 (308)

An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein [PDF]

, 2020
A vaccine protective against diverse HCV variants is needed to control the HCV epidemic. Structures of E2 complexes with front layer-specific broadly neutralizing antibodies (bNAbs) isolated from HCV-infected individuals, revealed a disulfide bond ...
Adams, Bailey, Battye, Chen, Chen, de Wildt, Dowd, Emsley, Evans, Flyak, Freedman, Hsu, Kabat, Kanyavuz, Keck, Kepler, Kong, Krause, Krissinel, Law, Logvinoff, Munshaw, Osburn, Reason, Sui, Swindells, Thomson, Tzarum, Wilson, Ying, Ying, Yusim, Zibbell   +32 more
core   +2 more sources

Neutralization tests with varicella-zoster virus [PDF]

Journal of Hygiene, 1969
SUMMARYA technique for neutralization tests using varicella-zoster virus propagated in primary human thyroid cells is described. The level of neutralizing antibody following chickenpox does not usually exceed a titre of 1/40 and in adults many years after infection it may be very low.
A E, Caunt, D G, Shaw
openaire   +2 more sources

Isotype specific ELISAs to detect antibodies against swine vesicular disease virus and their use in epidemiology [PDF]

, 2002
Isotype specific ELISAs to detect antibodies against swine vesicular disease, which may help to estimate the moment of infection, were developed and validated on sera from pigs experimentally infected with four different isolates of swine vesicular ...
Dekker, A., Hemert-Kluitenberg, F., van, Baars-Lorist, C.A., Terpstra, C.   +3 more
core   +2 more sources

A single, continuous metric to define tiered serum neutralization potency against HIV

eLife, 2018
HIV-1 Envelope (Env) variants are grouped into tiers by their neutralization-sensitivity phenotype. This helped to recognize that tier 1 neutralization responses can be elicited readily, but do not protect against new infections.
Peter Hraber, Bette Korber, Kshitij Wagh, David Montefiori, Mario Roederer   +4 more
doaj   +1 more source

Clinical Utility of SARS-CoV-2 Serological Testing and Defining a Correlate of Protection

Vaccines, 2023
Herein, we review established clinical use cases for SARS-CoV-2 antibody measures, which include diagnosis of recent prior infection, isolating high titer convalescent plasma, diagnosing multisystem inflammatory syndrome in children (MIS-C), and booster ...
Kimia Sobhani, Susan Cheng, Raquel A. Binder, Nicholas J. Mantis, James M. Crawford, Nkemakonam Okoye, Jonathan G. Braun, Sandy Joung, Minhao Wang, Gerard Lozanski, Christopher L. King, John D. Roback, Douglas A. Granger, Suresh B. Boppana, Amy B. Karger   +14 more
doaj   +1 more source

IgG antibodies against phospholipase A2 from Crotalus durissus terrificus: cross-reaction with venoms from Bothrops species from Argentina

Journal of Venomous Animals and Toxins including Tropical Diseases, 2009
We examined the ability of IgG anti-crotalic PLA2 to cross-react with Bothrops spp. venoms, from snakes found in the northeast of Argentina. Immunoblotting and ELISA tests showed that IgG anti-crotalic PLA2 recognize antigens of bothropic venoms ...
JP Rodríguez, MC De Marzi, S Maruñak, P Teibler, O Acosta, EL Malchiodi, LC Leiva   +6 more
doaj   +1 more source

A Recombinant Chimeric Cedar Virus-Based Surrogate Neutralization Assay Platform for Pathogenic Henipaviruses

Viruses, 2023
The henipaviruses, Nipah virus (NiV), and Hendra virus (HeV) can cause fatal diseases in humans and animals, whereas Cedar virus is a nonpathogenic henipavirus.
Moushimi Amaya, Randy Yin, Lianying Yan, Viktoriya Borisevich, Bishwo N. Adhikari, Andrew Bennett, Francisco Malagon, Regina Z. Cer, Kimberly A. Bishop-Lilly, Antony S. Dimitrov, Robert W. Cross, Thomas W. Geisbert, Christopher C. Broder   +12 more
doaj   +1 more source

Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea

Emerging Infectious Diseases, 2015
We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests.
Wan Beom Park, Ranawaka A.P.M. Perera, Pyoeng Gyun Choe, Eric H.Y. Lau, Seong Jin Choi, June Young Chun, Hong Sang Oh, Kyoung-Ho Song, Ji Hwan Bang, Eu Suk Kim, Hong Bin Kim, Sang Won Park, Nam Joong Kim, Leo Lit Man Poon, Ghazi Kayali, Myoung-don Oh   +15 more
doaj   +1 more source

Comprehensive Comparison of Seven SARS-CoV-2-Specific Surrogate Virus Neutralization and Anti-Spike IgG Antibody Assays Using a Live-Virus Neutralization Assay as a Reference

Microbiology Spectrum, 2023
Neutralizing antibodies (nAbs) are considered a valuable marker for measuring humoral immunity against SARS-CoV-2. However, live-virus neutralization tests (NTs) require high-biosafety-level laboratories and are time-consuming. Therefore, surrogate virus
Marianne Graninger, Claudia Maria Jani, Elisabeth Reuberger, Katja Prüger, Philipp Gaspar, David Niklas Springer, Christian Borsodi, Lisa Weidner, Susanne Rabady, Elisabeth Puchhammer-Stöckl, Christof Jungbauer, Eva Höltl, Judith Helene Aberle, Karin Stiasny, Lukas Weseslindtner   +14 more
doaj   +1 more source

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow, Calza, Chan, Cosma, De Jong, Farrohi, Ferrara, Fox, Frank, Fulton, Gross, Halloran, Harmon, Hierholzer, Johansson, Johansson, Kendal, Kilbourne, Montomoli, Okuno, O’Neill, Powers, Probert, Rowe, Schild, Schulman, Schulman, Scott, Sylte, Van Assen, Yewdell   +30 more
core   +3 more sources