Results 311 to 320 of about 358,601 (360)

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

Advanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang, Zhinang Yin, Yanqiong Shen, Gang Feng, Fangfang Dai, Dongyong Yang, Zhimin Deng, Jing Yang, Ruizhi Chen, Leifeng Yang, Xian Chen, Qing Sun, Chunyu Huang, Yanxiang Cheng, Hongbing Deng, Lianghui Diao, Longfei Li, Tailang Yin   +17 more
wiley   +1 more source

An efficient method for the selective isolation of feline herpesvirus 1(FHV-1) in feline calicivirus (FCV) coinfected specimens. [PDF]

BMC Vet Res
Zheng H, Yue H, Wang B, Yu X, Liu Y, Yu J, Zhang J, Han K, Han Y, Su H, Zhu H, Zhang X.   +11 more
europepmc   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

Moderately neutralizing epitopes in nonfunctional regions dominate the antibody response to Plasmodium falciparum EBA-140 [PDF]

, 2019
Adhikari, Jagat, Gross, Michael L., Paing, May M., Salinas, Nichole D., Tolia, Niraj   +4 more
core   +1 more source

Assessing anti-rabies vaccine response in humans: A rapid and high-throughput adaptable, pseudovirus-based neutralization assay as an alternative to rapid fluorescent focus inhibition test (RFFIT). [PDF]

PLoS Negl Trop Dis
Lupitha SS, Varghese GR, Das LJ, Prabhakaran P, Ananda AM, Mani RS, Sreekumar E.   +6 more
europepmc   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Antiviral activity of contact lens care solutions and rub-and-rinse regimen against adenovirus. [PDF]

Optom Vis Sci
Lourenco Nogueira C, Boegel SJ, Shukla M, Ngo W, Hui A, Jones LW, Aucoin MG.   +6 more
europepmc   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

A single mutation at position 214 of influenza B hemagglutinin enhances cross-neutralization. [PDF]

Emerg Microbes Infect
Cheng Z, Sun Y, Shen Y, Wu X, Pan L, Wu H, Bai Y, Zhao C, Ma J, Huang W.   +9 more
europepmc   +1 more source

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

Advanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao, Xi Cui, Shenglong Ding, Ketao Wang, Mingzhu Zhang   +4 more
wiley   +1 more source