Results 301 to 310 of about 1,846,702 (390)

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

Advanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu, Lin Jing, Yixin Li, Jinxing Zhou, Xiaohui Cui, Sen Li, Shijie Yang, Fangming Kan, Junfeng Du, Wentao Zhong, Sheng Yu, Ning Wang, Xing Jia, Junhui Li, Pan Nie, Zhenzhong Chen, Ying Han, Lingxi Jiang, Xiyun Yan, Hongxia Duan, Baiyong Shen   +20 more
wiley   +1 more source

Circulating neutralizing antibodies and SARS-CoV-2 variant replication following postvaccination infections. [PDF]

JCI Insight
Garcia-Knight MA, Kelly JD, Lu S, Tassetto M, Goldberg SA, Zhang A, Pineda-Ramirez J, Anglin K, Davidson MC, Chen JY, Fortes-Cobby M, Park S, Martinez A, So M, Donovan A, Viswanathan B, Richardson ET, McIlwain DR, Gaudilliere B, Rutishauser RL, Chenna A, Petropoulos C, Wrin T, Deeks SG, Abedi GR, Saydah S, Martin JN, Briggs Hagen M, Midgley CM, Peluso MJ, Andino R.   +30 more
europepmc   +1 more source

EPIZOOTIOLOGICAL STUDY ON EPIZOOTIC-FEVER-LIKE DISEASE OF CATTLE BY MEANS OF NEUTRALIZATION TEST : IV. NEUTRALIZING ANTIBODY RESPONSE TO LYOPHILIZED LIVE VIRUS VACCINE

, 1964
M. Yamada
openalex   +2 more sources

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Serological Correlate of Protection Established by Neutralizing Antibodies Differs Among Dialysis Patients with SARS-CoV-2 Variants of Concern. [PDF]

Vaccines (Basel)
Rostoker G, Rouanet S, Merzoug M, Chakaroun H, Griuncelli M, Loridon C, Boulahia G, Gagnon L.   +7 more
europepmc   +1 more source

Rusults of a Neutralizing Antibody Survey on Immunized Pigs without Clinical Manifestation in Some Piggery Contaminated with Hog Cholera Virus

, 1965
Atsushi Kawakubo, Togo Samejima, Morimasa FUJINO, Mario MURAMATSU, Hirozo SONOYAMA, Yuichi Mori   +5 more
openalex   +2 more sources

Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement [PDF]

, 2018
Diamond, Michael S, et al,, Fox, Julie M
core   +1 more source

CD103+ T Cells Eliminate Damaged Alveolar Epithelial Type II Cells Under Oxidative Stress to Prevent Lung Tumorigenesis

Advanced Science, EarlyView.
This work unravels a novel function of CD103+ T cells in eradicating oxidative‐stressed somatic cells to prevent lung tumorigenesis and identifies specific CD103+ T cell‐decline as a key feature in the aged lung. This comprehensive study highlights the contribution of immuno‐dysregulation to the high incidence of aging‐associated lung cancers ...
Yu Xu, Haorui Luo, Jiahao Wang, Haifeng Liu, Luonan Chen, Hongbin Ji, Zimu Deng, Xiaolong Liu   +7 more
wiley   +1 more source

Relevance of Neutralizing Antibodies for the Pharmacokinetics of Pegunigalsidase Alfa in Patients with Fabry Disease. [PDF]

BioDrugs
Lenders M, Menke ER, Rudnicki M, Cybulla M, Brand E.   +4 more
europepmc   +1 more source

EPIZOOTIOLOGICAL STUDY ON EPIZOOTIC-FEVER-LIKE DISEASE OF CATTLE BY MEANS OF NEUTRALIZATION TEST : III. NEUTRALIZING ANTIBODY RESPONSE IN THE EPIZOOTIC SEASON IN 1961

, 1964
Shinji YAMADA
openalex   +2 more sources