Results 121 to 130 of about 289,824 (354)

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa, Ana Marote, Catarina Barbosa, Jonas Campos, António J. Salgado, Jana B. Nieder   +5 more
wiley   +1 more source

Neutralizing antibodies in convalescent patients [PDF]

Nature Reviews Immunology, 2020
Uhl, LFK, Chauveau, A
openaire   +3 more sources

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Studies of Complement-Fixing and Neutralizing Antibodies against Certain Adenoviruses [PDF]

, 1957
Sidney Katz, William S. Jordan, George F. Badger, John H. Dingle   +3 more
openalex   +1 more source

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

Advanced Healthcare Materials, Volume 14, Issue 17, July 4, 2025.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang, Zhaoyu Chen, Ruihao Yang, Ziga Luogu, Qian Ren, Hao Hu, Kaixin Wang, Senlin Li, Changlin Deng, Meng Li, Lu Zheng   +10 more
wiley   +1 more source

Cryo-EM structures of HCV E2 glycoprotein bound to neutralizing and non-neutralizing antibodies determined using bivalent Fabs as fiducial markers

Communications Biology
Global elimination of hepatitis C virus (HCV) will require an effective cross-genotype vaccine. The HCV E2 envelope glycoprotein is the main target of neutralizing antibodies but also contains epitopes that elicit non-neutralizing antibodies which may ...
Salman Shahid, Sharanbasappa S. Karade, S. Saif Hasan, Rui Yin, Liqun Jiang, Yanxin Liu, Nathaniel Felbinger, Liudmila Kulakova, Eric A. Toth, Zhen-Yong Keck, Steven K. H. Foung, Thomas R. Fuerst, Brian G. Pierce, Roy A. Mariuzza   +13 more
doaj   +1 more source

Deep immunoglobulin repertoire sequencing depicts a comprehensive atlas of spike-specific antibody lineages shared among COVID-19 convalescents

Emerging Microbes and Infections
Neutralizing antibodies are a key component in protective humoral immunity against SARS-CoV-2. Currently, available technologies cannot track epitope-specific antibodies in global antibody repertoires. Thus, the comprehensive repertoire of spike-specific
Qihong Yan, Yudi Zhang, Ruitian Hou, Wenjing Pan, Huan Liang, Xijie Gao, Weiqi Deng, Xiaohan Huang, Linbing Qu, Congli Tang, Ping He, Banghui Liu, Qian Wang, Xinwei Zhao, Zihan Lin, Zhaoming Chen, Pingchao Li, Jian Han, Xiaoli Xiong, Jincun Zhao, Song Li, Xuefeng Niu, Ling Chen   +22 more
doaj   +1 more source

The titration of vaccinial neutralizing antibody on chorio-allantoic membranes [PDF]

, 1957
Etienne Boulter
openalex   +1 more source

Tackling influenza with broadly neutralizing antibodies

Current Opinion in Virology, 2017
Monoclonal antibodies have revolutionized the treatment of several human diseases, including cancer, autoimmunity and inflammatory conditions and represent a new frontier for the treatment of infectious diseases. In the last decade, new methods have allowed the efficient interrogation of the human antibody repertoire from influenza immune individuals ...
Nicole L. Kallewaard, Barbara Guarino, Davide Corti, Antonio Lanzavecchia, Elisabetta Cameroni, Qing Zhu   +5 more
openaire   +2 more sources

Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro

Advanced Healthcare Materials, EarlyView.
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski, Svenja Nellinger, Franziska Brigitte Albrecht, Petra Juliane Kluger   +3 more
wiley   +1 more source