Results 121 to 130 of about 300,221 (330)

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model [PDF]

, 2017
James E. Voss, Raiees Andrabi, Laura E. McCoy, Natalia de Val, Roberta Fuller, Terrence Messmer, Ching-Yao Su, Devin Sok, Salar N. Khan, Fernando Garcés, Laura K. Pritchard, Richard T. Wyatt, Andrew B. Ward, Max Crispin, Ian A. Wilson, Dennis R. Burton   +15 more
openalex   +1 more source

Prevalence of Zika virus neutralizing antibodies in healthy adults in Vietnam during and after the Zika virus epidemic season: a longitudinal population-based survey [PDF]

, 2020
Co Thach Nguyen, Meng Ling Moi, Thi Quynh Mai Le, Thi Thu Thuy Nguyen, Vu Thi Bich Hau, Hai Tuan Nguyen, Thi Thu Hang Pham, Thi Hien Thu Le, Le Manh Hung Nguyen, Minh Huong Phu Ly, Chris Fook Sheng Ng, Taichiro Takemura, Kouichi Morita, Futoshi Hasebe   +13 more
openalex   +1 more source

Bone‐Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A tunable methacrylated decellularized bone matrix hydrogel (dECM‐MA) is developed to support 3D culture of human osteoblasts. The hydrogel preserves bone‐specific ECM cues and allows precise control over mechanical properties. This system provides a customizable platform for studying osteogenic differentiation and modeling bone tissue environments for
Minne Dekker, Luke Hipwood, Akhilandeshwari Ravichandran, Dietmar W. Hutmacher, Christoph Meinert, Jacqui McGovern   +5 more
wiley   +1 more source

Deep immunoglobulin repertoire sequencing depicts a comprehensive atlas of spike-specific antibody lineages shared among COVID-19 convalescents

Emerging Microbes and Infections
Neutralizing antibodies are a key component in protective humoral immunity against SARS-CoV-2. Currently, available technologies cannot track epitope-specific antibodies in global antibody repertoires. Thus, the comprehensive repertoire of spike-specific
Qihong Yan, Yudi Zhang, Ruitian Hou, Wenjing Pan, Huan Liang, Xijie Gao, Weiqi Deng, Xiaohan Huang, Linbing Qu, Congli Tang, Ping He, Banghui Liu, Qian Wang, Xinwei Zhao, Zihan Lin, Zhaoming Chen, Pingchao Li, Jian Han, Xiaoli Xiong, Jincun Zhao, Song Li, Xuefeng Niu, Ling Chen   +22 more
doaj   +1 more source

Neutralizing antibody detection v1

, 2020
Neutralizing antibodies of serum samples were detected by 90% plaque reduction neutralization test (PRNT90).
Shihong Fu, Wenjing Liu
openaire   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

SARS-CoV-2 neutralizing camelid heavy-chain-only antibodies as powerful tools for diagnostic and therapeutic applications [PDF]

, 2022
Anja Schlör, Stefan Hirschberg, Ghada Ben Amor, Toni Luise Meister, Prerna Arora, Stefan Pöhlmann, Markus Hoffmann, Stephanie Pfaender, Omar Kamal Eddin, Julian Kamhieh‐Milz, Katja Hanack   +10 more
openalex   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Cryo-EM structures of HCV E2 glycoprotein bound to neutralizing and non-neutralizing antibodies determined using bivalent Fabs as fiducial markers

Communications Biology
Global elimination of hepatitis C virus (HCV) will require an effective cross-genotype vaccine. The HCV E2 envelope glycoprotein is the main target of neutralizing antibodies but also contains epitopes that elicit non-neutralizing antibodies which may ...
Salman Shahid, Sharanbasappa S. Karade, S. Saif Hasan, Rui Yin, Liqun Jiang, Yanxin Liu, Nathaniel Felbinger, Liudmila Kulakova, Eric A. Toth, Zhen-Yong Keck, Steven K. H. Foung, Thomas R. Fuerst, Brian G. Pierce, Roy A. Mariuzza   +13 more
doaj   +1 more source

Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIV_smm/mac Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization

mBio, 2019
As a consequence of their independent evolutionary origins in apes and Old World monkeys, human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency viruses of the SIVsmm/mac lineage express phylogenetically and antigenically distinct ...
Benjamin von Bredow, Raiees Andrabi, Michael Grunst, Andres G. Grandea, Khoa Le, Ge Song, Zachary T. Berndsen, Katelyn Porter, Jesper Pallesen, Andrew B. Ward, Dennis R. Burton, David T. Evans   +11 more
doaj   +1 more source