Results 121 to 130 of about 1,881,376 (382)

Characterization of monoclonal and polyclonal antibodies to bovine enteric coronavirus: Establishment of an efficient ELISA for antigen detection in feces [PDF]

, 1989
Monoclonal antibodies to bovine enteric coronavirus (BEC) were produced. Additionally, polyclonal antibodies were made in rabbits and guinea pigs and extracted from the yolk of immunized hens.
Czerny, C. P., Eichhorn, Werner
core   +1 more source

SARS-CoV-2-Neutralizing Antibodies

Vaccines
The COVID-19 pandemic, triggered by the SARS-CoV-2 virus, has profoundly and permanently affected many aspects of the world [...]
Yawen Liu, Jianhui Nie
openaire   +3 more sources

High neutralizing antibody titer in intensive care unit patients with COVID-19

Emerging Microbes and Infections, 2020
Coronavirus disease 2019 (COVID-19) has a wide spectrum of disease severity from mild upper respiratory symptoms to respiratory failure. The role of neutralizing antibody (NAb) response in disease progression remains elusive.
Li Liu, K. To, Kwok-Hung Chan, Y. Wong, R. Zhou, Ka-Yi Kwan, C. Fong, Lin-lei Chen, C. Y. Choi, Lu Lu, O. Tsang, W. Leung, W. To, I. Hung, K. Yuen, Zhiwei Chen   +15 more
semanticscholar   +1 more source

Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction

Advanced Functional Materials, EarlyView.
This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko, Hyeon‐Jin Kim, Jeong‐Uk Kim, Seh Ri Oh, Tae Hoon Kang, Junghwan Byun, Uk‐Jae Lee, Minglin Ma, Su‐Hwan Kim, Byung‐Gee Kim, Nathaniel S. Hwang   +10 more
wiley   +1 more source

Combining a rhesus cytomegalovirus/SIV vaccine with a neutralizing antibody to protect against SIV challenges in rhesus macaques

Frontiers in Microbiology
A vaccine is considered essential for controlling the HIV pandemic and ultimately eradicating AIDS. Neutralizing antibodies and MHC-E-restricted CD8+ T cells have shown the ability to protect against the simian counterpart of HIV, SIV, in rhesus macaques.
Jessica Coppola, Mara Parren, Raiza Bastidas, Karen Saye, Jacqueline Malvin, Joseph G. Jardine, Roxanne M. Gilbride, Sohita Ojha, Shana Feltham, David Morrow, Aaron Barber-Axthelm, Rachele Bochart, Randy Fast, Kelli Oswald, Rebecca Shoemaker, Jeffrey D. Lifson, Louis J. Picker, Dennis R. Burton, Scott G. Hansen   +18 more
doaj   +1 more source

Reprogramming the antigen specificity of B cells using genome-editing technologies

eLife, 2019
We have developed a method to introduce novel paratopes into the human antibody repertoire by modifying the immunoglobulin (Ig) genes of mature B cells directly using genome editing technologies. We used CRISPR-Cas9 in a homology directed repair strategy,
James E Voss, Alicia Gonzalez-Martin, Raiees Andrabi, Roberta P Fuller, Ben Murrell, Laura E McCoy, Katelyn Porter, Deli Huang, Wenjuan Li, Devin Sok, Khoa Le, Bryan Briney, Morgan Chateau, Geoffrey Rogers, Lars Hangartner, Ann J Feeney, David Nemazee, Paula Cannon, Dennis R Burton   +18 more
doaj   +1 more source

Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants [PDF]

, 2021
Tingting Li, Wenhui Xue, Qingbing Zheng, Shuo Song, Chuanlai Yang, Hualong Xiong, Sibo Zhang, Minqing Hong, Yali Zhang, Hai Yu, Yuyun Zhang, Hui Sun, Yang Huang, Tingting Deng, Xin Chi, Jinjin Li, Shaojuan Wang, Lizhi Zhou, Tingting Chen, Yingbin Wang, Tong Cheng, Tianying Zhang, Quan Yuan, Qinjian Zhao, Jun Zhang, Jason S. McLellan, Z. Hong Zhou, Zheng Zhang, Shaowei Li, Ying Gu, Ningshao Xia   +30 more
openalex   +1 more source

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

Nature Medicine, 2021
D. Khoury, D. Cromer, A. Reynaldi, T. Schlub, A. Wheatley, J. Juno, K. Subbarao, S. Kent, J. Triccas, M. Davenport   +9 more
semanticscholar   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Functional stability of HIV-1 envelope trimer affects accessibility to broadly neutralizing antibodies at its apex [PDF]

, 2017
The trimeric envelope glycoprotein spike (Env) of HIV-1 is the target of vaccine development to elicit broadly neutralizing antibodies (bnAbs). Env trimer instability and heterogeneity in principle make subunit interfaces inconsistent targets for the ...
Gift, Syna Kuriakose, Kim, Arthur S, Leaman, Daniel P, Zhang, Lei, Zwick, Michael B   +4 more
core   +2 more sources