Results 181 to 190 of about 300,221 (330)

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

HIV Superinfection Drives De Novo Antibody Responses and Not Neutralization Breadth [PDF]

, 2018
Daniel J. Sheward, Jinny C. Marais, Valerie Bekker, Ben Murrell, Kemal Eren, Jinal N. Bhiman, Molati Nonyane, Nigel Garrett, Zenda Woodman, Quarraisha Abdool Karim, Salim S. Abdool Karim, Lynn Morris, Penny L. Moore, Carolyn Williamson   +13 more
openalex   +1 more source

Replacing BPA: Structural Substitutes BPAF Binding to the Progesterone Receptor Elevates Breast Cancer Risk

Advanced Science, EarlyView.
This study demonstrates that bisphenol analogues, particularly BPAF, bind to progesterone receptor, promoting breast cancer cell proliferation, migration, and mammary tumor growth, indicating that bisphenol A substitutes may pose equal or greater health risks.
Xiaotong Ji, Peilin Li, Haoyang Wu, Linzhuo Shen, Xiaoyun Wu, Peiyun Jiang, Yating Li, Xiaozheng Zhang, Huifeng Yue   +8 more
wiley   +1 more source

Does the Chimerization Process Affect the Immunochemical Properties of WNV-Neutralizing Antibody 900? [PDF]

Int J Mol Sci
Isaeva AA, Nesmeyanova VS, Shanshin DV, Ushkalenko ND, Volosnikova EA, Esina TI, Protopopova EV, Svyatchenko VA, Loktev VB, Olkin SE, Danilenko ED, Kazachinskaia EI, Shcherbakov DN.   +12 more
europepmc   +1 more source

IgG3 snitcher of RSV infections in the very young [PDF]

, 2017
Saelens, Xavier, Schepens, Bert
core   +3 more sources

Comparison of Two High-Throughput Assays for Quantification of Adenovirus Type 5 Neutralizing Antibodies in a Population of Donors in China

, 2012
Qiang Liu, Jianhui Nie, Weijin Huang, Shufang Meng, Bao‐Zhu Yuan, Dongying Gao, Xuemei Xu, Youchun Wang   +7 more
openalex   +2 more sources

Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration

Advanced Science, EarlyView.
Through a genetic screen, PKN2 and MOB4 are identified as two proteins regulating the healing of an epithelial model wound. PKN2 promotes collective cell migration by maintaining the cohesion of cell monolayers from their lateral junctions, whereas MOB4 restrains collective cell migration and provides a lamellipodial cue for front‐rear polarity in ...
Artem I. Fokin, Yueying Lin, Dmitry Y. Guschin, Hsiang‐Ying Chen, John James, Jie Yan, Pascal Silberzan, Alexis M. Gautreau   +7 more
wiley   +1 more source

Zika Virus Neutralizing Antibody Responses Elicited by Vaccination or Infection. [PDF]

Open Forum Infect Dis
Galindo CM, Ling Y, Kpamegan E, Nascimento EJM, Perez-Guzman E, Ticona JPA, Chan KF, Castanha P, Buddhari D, Farmer A, Fernandez S, Baldwin WR, Kaiser M, Fernandes J, Zahralban-Steele M, Brinkman A, Rindfleisch T, Moss KJ, Rouphael N, El Sahly HM, Marques ETA, Ko AI, Acosta CJ.   +22 more
europepmc   +1 more source

Functional Optimization of Broadly Neutralizing HIV-1 Antibody 10E8 by Promotion of Membrane Interactions [PDF]

, 2018
Edurne Rujas, Daniel P. Leaman, Sara Insausti, Lei Ortigosa-Pascual, Lei Zhang, Michael B. Zwick, José L. Nieva   +6 more
openalex   +1 more source

PHR‐Mediated Pi Starvation Response Mobile Messenger RNAs Represent Noncoding Transcripts in Recipient Tissues

Advanced Science, EarlyView.
Mobile messenger RNAs (mRNAs) can travel long distances, serving as systemic signals that participate in plant growth and stress acclimation. This work determines that PHR proteins mediate the Pi starvation response (PSR)‐specific long‐distance transport of mRNAs and that these PSR‐specific mobile mRNAs represent noncoding transcripts in recipient ...
Weiguo Dong, Shuman Wang, Chao Liu, Lulu Qiao, Kai Liu, Qiongli Jin, Xiaorong Mo, Xingxing Shen, Keke Yi, Zhiye Wang   +9 more
wiley   +1 more source