Results 181 to 190 of about 1,881,376 (382)

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Additional file 4 of Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants

, 2021
Chunyan Yi, Xiaoyu Sun, Yixiao Lin, Chenjian Gu, Longfei Ding, Xiao Lu, Zhuo Yang, Yaguang Zhang, Liyan Ma, Wangpeng Gu, Aidong Qu, Xu Zhou, Xiuling Li, Jianqing Xu, Zhiyang Ling, Youhua Xie, Hongzhou Lu, Bing Sun   +17 more
openalex   +1 more source

A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity [PDF]

, 2021
Vincent Legros, Solène Denolly, Manon Vogrig, Bertrand Boson, Eglantine Siret, Josselin Rigaill, Sylvie Pillet, Florence Grattard, Sylvie Gonzalo, Paul O. Verhoeven, Omran Allatif, P. Berthelot, Carole Pélissier, Guillaume Thiéry, Élisabeth Botelho-Nevers, Guillaume Y. Millet, Jérôme Morel, Stéphane Paul, Thierry Walzer, François–Loïc Cosset, Thomas Bourlet, Bruno Pozzetto   +21 more
openalex   +1 more source

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng, Heyan Huang, Xiangru Chen, Jie Fu, Zhiwei Sun, Mengjuan Tao, Jianwei Mao, Fei Zhang, Zhou Wan, Yuan Li, Dingan Wu, Chuchao Zhou, Yanqing Yang   +12 more
wiley   +1 more source

Evidence for the presence of streptococcal-superantigen-neutralizing antibodies in normal polyspecific immunoglobulin G [PDF]

, 1996
Anna Norrby‐Teglund, Rupert Kaul, Donald E. Low, Allison McGeer, Jan Andersson, Jan Andersson, Malak Kotb   +6 more
openalex   +1 more source

High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape

Nature, 2021
F. Schmidt, Y. Weisblum, Magda Rutkowska, D. Poston, Justin DaSilva, Fengwen Zhang, Eva Bednarski, A. Cho, Dennis J. Schaefer-Babajew, C. Gaebler, M. Caskey, M. Nussenzweig, T. Hatziioannou, P. Bieniasz   +13 more
semanticscholar   +1 more source

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

Clearance of a persistent paramyxovirus infection is mediated by cellular immune responses but not by serum-neutralizing antibody [PDF]

, 1990
D. F. Young, Richard E. Randall, J. Hoyle, B.E. Souberbielle   +3 more
openalex   +1 more source

Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Hyperimmune Immunoglobulin Demonstrates Potent Neutralization and Antibody-Dependent Cellular Cytotoxicity and Phagocytosis Through N and S Proteins [PDF]

, 2021
José María Soberanes Díez, Carolina S. Romero, Maria Cristina Cruz, Peter Vandeberg, W. Keither Merritt, Edwards Pradenas, Benjamin Trinité, Julià Blanco, Bonaventura Clotet, Todd Willis, Rodrigo Gajardo   +10 more
openalex   +1 more source

COVID‐19: are neutralizing antibodies neutralizing enough? [PDF]

Transfusion, 2020
openaire   +2 more sources