Results 241 to 250 of about 1,881,376 (382)

Identification of CD4-Binding Site Dependent Plasma Neutralizing Antibodies in an HIV-1 Infected Indian Individual

, 2015
Lubina Khan, Muzamil Ashraf Makhdoomi, Sanjeev Kumar, Ambili Nair, Raiees Andrabi, Brenda E. Clark, Kate Auyeung, Jayanta Bhattacharya, Madhu Vajpayee, Naveet Wig, Ralph Pantophlet, Kalpana Luthra   +11 more
openalex   +2 more sources

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Impacts of neutralizing antibody responses on SARS-CoV-2 evolution and its associated disease progression. [PDF]

Immun Inflamm
Wang L, Aliyari S, Sands N, Lee B, Yu A, Xia S, Jolkovsky EL, Zhang S, Kim J, Cheng G.   +9 more
europepmc   +1 more source

Evidence for Potent Autologous Neutralizing Antibody Titers and Compact Envelopes in Early Infection with Subtype C Human Immunodeficiency Virus Type 1

, 2007
Bing Li, Julie M. Decker, Roy W. Johnson, Frédéric Bibollet‐Ruche, Xiping Wei, Joseph Mulenga, Susan Allen, Eric Hunter, Beatrice H. Hahn, George M. Shaw, Jerry L. Blackwell, Cynthia A. Derdeyn   +11 more
openalex   +2 more sources

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Sero-neutralizing antibody against orthopoxviruses in populations of Wuhan, China. [PDF]

Mol Biomed
Gao Z, Liu T, Zhao Z, Wang B, Hou L.
europepmc   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Finally neutralizing the threat? A novel SARS-CoV-2 vaccine platform that elicits enhanced neutralizing antibody responses

Daniel J. Salamango
openalex   +1 more source

Corrigendum: A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection [PDF]

Ping Li, Ziyi Jiang, Jingjing Shi, Hongying Sha, Zihang Yu, Yan Zhao, Sanyang Han, Lan Ma   +7 more
openalex   +1 more source

Understanding the Acceptability of Broadly Neutralizing Antibodies for HIV Prevention Among At-Risk Populations and Feasibility Considerations for Product Introduction in India: Protocol for a Qualitative Study (Preprint)

, 2023
Joyeeta Mukherjee, Shruta Rawat, Saif ul Hadi, Pritha Aggarwal, Venkatesan Chakrapani, Pratyasha Rath, Pallavi Manchi, Aylur K. Srikrishnan, Shelly Malhotra, Margaret Keane, Alok Gangaramany   +10 more
openalex   +1 more source