Results 241 to 250 of about 300,221 (330)

Neutralizing Antibody Response Characteristics in Elderly Patients with SARS-CoV-2 Infection and Their Association with Clinical Phenotypes. [PDF]

Vaccines (Basel)
Li Y, Wang L, Ma J, Geng W, Wang Y.
europepmc   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Assessment of SARS-CoV-2 neutralizing antibody persistence using LFIC: a prevalence study after booster doses. [PDF]

BMC Public Health
Montagud AC, Moragues R, Gabaldón-Bravo EM, Hurtado-Sánchez JA, Tuells J.   +4 more
europepmc   +1 more source

Human Immunodeficiency Virus Type 1 Escape from Cyclotriazadisulfonamide-Induced CD4-Targeted Entry Inhibition Is Associated with Increased Neutralizing Antibody Susceptibility

, 2009
Kurt Vermeire, Kristel Van Laethem, Wouter Janssens, Thomas W. Bell, Dominique Schols   +4 more
openalex   +2 more sources

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato

Advanced Science, EarlyView.
The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian, Mingjun Li, Xiaojia Huang, Markus Wirtz, Xiaohui Zheng, Shilong Fan, Jiang Tian, Shaoqun Liu, Zhonghua Liu, Hongbo Zhao   +9 more
wiley   +1 more source

Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025. [PDF]

Virus Evol
Kikawa C, Huddleston J, Loes AN, Turner SA, Lee J, Barr IG, Cowling BJ, Englund JA, Greninger AL, Harvey R, Hasegawa H, Ho F, Lacombe K, Leung NHL, Lewis NS, Peck H, Watanabe S, Smith DJ, Bedford T, Bloom JD.   +19 more
europepmc   +2 more sources

Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2. [PDF]

J Exp Med
Changrob S, Yasuhara A, Park S, Bangaru S, Li L, Troxell CA, Halfmann PJ, Erickson SA, Catanzaro NJ, Yuan M, Zhou P, Huang M, Wilbanks GD, McGrath JJC, Singh G, Nelson SA, Fu Y, Zheng NY, Carayannopoulos SM, Dugan HL, Shaw DG, Stamper CT, Madariaga MLL, Krammer F, Andrabi R, Burton DR, Ward AB, Wilson IA, Kawaoka Y, Wilson PC.   +29 more
europepmc   +1 more source

Bifurcate Regulation of Hematopoietic Homeostasis and Bone Osteogenesis by VHL‐HIF2α‐Controlled Adipocyte Function

Advanced Science, EarlyView.
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li, Jia Li, Anshu Tang, Cong Li, Chao Zhang, Congcong Zhang, Yun‐Cai Liu   +6 more
wiley   +1 more source

Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates. [PDF]

Sci Immunol
Sutton HJ, Ma KM, Steichen JM, Schiffner T, Altheide TK, Liguori A, Lu D, Kubitz M, Georgeson E, Phelps N, Tingle R, Alavi NB, Ben-Akiva E, Zhou X, Kifude C, Flynn CT, Rakasz E, Irvine DJ, Schief WR, Crotty S.   +19 more
europepmc   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source