Results 281 to 290 of about 1,804,185 (380)

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

open access: yesAdvanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li   +8 more
wiley   +1 more source

Evaluation of Reactogenicity and Neutralizing Antibody Responses 6 Months Post-Vaccination with Monovalent COVID-19 Vaccine. [PDF]

open access: yesInfect Chemother
Lim SY   +12 more
europepmc   +1 more source

Neutralizing antibody responses to varicella-zoster virus [PDF]

open access: bronze, 1975
Nathalie J. Schmidt, E. H. Lennette
openalex   +1 more source

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

open access: yesAdvanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo   +15 more
wiley   +1 more source

Neutralizing antibody response to different COVID-19 vaccines in Brazil: the impact of previous infection and booster doses. [PDF]

open access: yesFront Immunol
Caetano BLL   +14 more
europepmc   +1 more source

Complement-Requiring Neutralizing Antibodies in Hyperimmune Sera to Human Cytomegaloviruses [PDF]

open access: bronze, 1971
B Graham   +4 more
openalex   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

open access: yesAdvanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu   +5 more
wiley   +1 more source

Plasmodium falciparum Parasitemia Does Not Diminish Neutralizing Antibody Responses After mRNA COVID-19 Booster Vaccination in HIV-infected Adults. [PDF]

open access: yesJ Infect Dis
Samandari T   +20 more
europepmc   +1 more source

Late 19S Rabbit Antibody Neutralization Test for Differentiating Herpes Simplex Virus Types 1 and 2 [PDF]

open access: bronze, 1970
Berge Hampar   +3 more
openalex   +1 more source

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